Immunocontraception of Male and Female Giraffes Using the GnRH Vaccine Improvac® [PDF]
I Protocols for contraception using the GnRH vaccine Improvac® were developed. A clear reduction of fecal hormone metabolites in female giraffes was achieved with three, and in males with four or five injections at 4‐week intervals. Effective booster injections were administered at 2‐month intervals in the first, and at three to 4‐month intervals in ...
Franz Schwarzenberger +2 more
exaly +7 more sources
Improvac Immunocastration Affects the Development of Thigh Muscles but Not Pectoral Muscles in Male Chickens [PDF]
Improvac has been tentatively used to immune-castrate roosters. The aim of this study was to investigate whether Improvac affected skeletal muscle development in chickens.
Y.T. Zeng +10 more
exaly +6 more sources
Early Vaccination With Improvac®: Effects on Performance and Behaviour of Male Pigs
The aim of this study was to investigate the effect of giving a two-dose regimen of gonadotropin-releasing hormone vaccine, Improvac® (Pfizer Ltd), earlier than currently recommended, on performance and behaviour of growing/finishing pigs.
Galia Zamaratskaia +2 more
exaly +6 more sources
Immunization against Gonadotropin-Releasing Hormone in Female Beef Calves to Avoid Pregnancy at Time of Slaughter [PDF]
Precocious puberty in beef heifers can result in unwanted pregnancies due to accidental breeding by farm bulls. Inbreeding, premature calving followed by dystocia and a high stillbirth rate or slaughtering of pregnant heifers are the consequences of this
Julia Schütz +5 more
doaj +8 more sources
Effect of the biological castration vaccine (Improvac®) on sex hormones and reproductive organs of pigs in Vietnam [PDF]
The Improvac® vaccine has been shown to improve growth performance, meat quality, and sexual behavior in swine herds in several countries. This study initially investigated the ability of this vaccine to control sex hormones and the development ...
Danh Cong Lai +5 more
doaj +3 more sources
Histological Findings in Testes of Baboons (Papio spp.) and Dwarf Bucks (Capra hircus) Subject to Repeated Immunisation Against GnRH [PDF]
Background Immunocontraception is a population management strategy based on vaccines that induce an immune response against reproductive targets such as GnRH.
Teresa Ferrín +8 more
doaj +3 more sources
Influences of Immunocastration on Endocrine Parameters, Growth Performance and Carcass Quality, as Well as on Boar Taint and Penile Injuries [PDF]
Castration of male pigs without anesthesia is a significant welfare issue. Improvac®, a GnRH vaccine induces an endogenous immune response leading to a decrease in testicular steroids.
Susanne Zoels +8 more
doaj +4 more sources
For centuries, entire male pigs have been castrated to reduce the risk of boar taint. However, physical castration of pig is increasingly being questioned with regard to animal welfare considerations. Immunization against gonadotrophin releasing hormone (
N. Quiniou +4 more
exaly +5 more sources
Long-Term Immunocastration Protocols Successfully Reduce Testicles’ Size in Bísaro Pigs [PDF]
This study aimed to find a suitable immunocastration protocol for male Bísaro pigs (BP) due to the breed and production system particularities. Twenty-five male BP were treated with Improvac® according to three protocols: using two (GrpE2 and L2) or ...
Gustavo Paixão +5 more
doaj +2 more sources
[Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study]. [PDF]
INTRODUCTION The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows.
Hirsbrunner, Gabriela +5 more
core +5 more sources

