Results 111 to 120 of about 7,027,976 (306)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Factors Improving Oncology Nurse Role Performance in Providing Pediatric Palliative Care: A SWOT Analysis. [PDF]

open access: yesAsian Pac J Cancer Prev, 2023
Pouy S   +4 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A performance in two halves

open access: yes
2 day residency and performance at Sonic Arts Centre (Univ. of Belfast), as part of the Sonorities Festival. Panos Ghikas, Wobbly (Jon Leidecker) and Jennifer Walshe join forces for a performance in two halves.
Ghikas, P.
core  

The role of logistics in performance management

open access: yesMontenegrin Journal of Economics, 2009
Apart from the proven and significant role of logistics in integrating marketing and management systems of a company, the position on the connection between the logistics and institutional (top) level of a business strategy in contemporary literature and business practice is being acknowledged.
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Performance Management and Performance Measurement in the Education Sector [PDF]

open access: yes
The paper examines several outstanding issues on the interface between the measurement of performance in primary and secondary education and the management of improved performance in this nationally important sector.
David Mayston
core  

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