Results 121 to 130 of about 1,274,468 (311)

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

Phase‐Resolved Defect Transport Mechanisms Governing Asynchronous Ordering in a Eutectic High‐Entropy Alloy

Advanced Science, EarlyView.
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao, Qingshuang Ma, Jie Xiong, Jing Bai, Huijun Li, Qiuzhi Gao   +5 more
wiley   +1 more source

Discovering the literacy gap: A systematic review of reading and writing theories in research

Cogent Education, 2016
Research is failing to consistently report theoretical frameworks, increasing the gap between research and practice, and increasing the difficulty teachers face in effectively matching interventions with student needs.
Tracey S. Hodges, Luxi Feng, Li-Jen Kuo, Erin McTigue   +3 more
doaj   +1 more source

Coping, Confidence and Alienation: the early experience of trainee teachers in English FE

, 2012
This article examines what both in-service and pre-service trainee teachers learn from their early experience of teaching in further education (FE) colleges in England.
Orr, Kevin, Kevin Orr
core   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

TPACK: exploring a secondary pre-service teachers' context

, 2013
Twenty-first century teacher educators need to design learning experiences integrating technology for transformative learning. Bringing together the power of deep content knowledge, pedagogical knowledge and technological knowledge in an integrated ...
Lock, Jennifer, Redmond, Petrea
core  

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design

Advanced Science, EarlyView.
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram, Mohit Chakraborty, Sai Mani Kumar Devathi, B. Pabitramohan Prusty, Rohit Batra   +4 more
wiley   +1 more source

Mathematics teachers’ career length and teaching self-efficacy

Frontiers in Education
The influence of teachers’ self-efficacy on the effectiveness of teaching is well-documented in educational research. The aim of this study was to investigate the construct of self-efficacy in mathematics teachers.
Monika Grigaliuniene, Erno Lehtinen, Erno Lehtinen, Erno Lehtinen   +3 more
doaj   +1 more source

Pre-service teachers' understanding of child abuse and their professional role in child protection

, 2008
Universities play an integral role in training teachers in the areas of understanding and preparedness to deal with child abuse and neglect while at the same time advocating for the 'rights of the child'. Unfortunately pre-service teachers are at risk of
Brown, Alice
core  

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source