Results 41 to 50 of about 497,128 (308)

Corrigendum: Functional and structural analysis of missense variants in the human PDCD1 Gene

Journal of Public Health in Africa
No abstract available.
Hanâ Baba, Meryem Bouqdayr, Asmae Saih, Benson R. Kidenya, Mohamed A. Sesay, Simpson Addo, Lahcen Wakrim, Anass Kettani   +7 more
doaj   +1 more source

Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy. [PDF]

, 2015
Background: Hypertrophic cardiomyopathy (HCM) is a common genetic heart disorder characterized by unexplained left ventricle hypertrophy associated with non-dilated ventricular chambers.
BOTTILLO, IRENE, CAPUTO, VIVIANA, Castori, M, D'ANGELANTONIO, DANIELA, De Bernardo, C, Giannarelli, D, GRAMMATICO, Paola, LIPARI, MARTINA, Majore, S, PAIARDINI, ALESSANDRO, PIZZUTI, Antonio, Re, F, Zachara, E   +12 more
core   +1 more source

The benefits of in silico modeling to identify possible small-molecule drugs and their off-target interactions [PDF]

, 2018
Accepted for publication in a future issue of Future Medicinal Chemistry.The research into the use of small molecules as drugs continues to be a key driver in the development of molecular databases, computer-aided drug design software and collaborative ...
Blomberg N, Choi SH, Hastings J, Hirschey J, Mire Zloh, Stewart B Kirton, Wang X   +6 more
core   +2 more sources

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]

, 2010
Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T., Breitling, Rainer, HASH(0x55aa09327868), Hodgson, D. A., Merlo, Maria E., Takano, Eriko, Wellington, E. M. H.   +6 more
core   +10 more sources

In-Silico prediction and characterization of Elephant endotheliotropic herpesvirus proteins for development of immunodiagnostics

Environment Conservation Journal
Elephant Endotheliotropic Herpesvirus (EEHV) is a major cause of fatal hemorrhagic disease in juvenile elephants, highlighting the urgent need for reliable serological diagnostic tools for early detection and epidemiological surveillance. Effective EEHV
Kirtika Sharma, K. G. Sai Balaji, Karikalan Mathesh, Pracheta Janmeda, Gaurav Kumar Sharma   +4 more
doaj   +1 more source

Luteolin-Fabricated ZnO Nanostructures Showed PLK-1 Mediated Anti-Breast Cancer Activity

Biomolecules, 2021
The present work describes a facile and convenient procedure for synthesizing zinc oxide nanoparticles using luteolin isolated from Eclipta alba plant (L-ZnONPs) at room temperature.
Shiva Prasad Kollur, Shashanka K. Prasad, Sushma Pradeep, Ravindra Veerapur, Sharanagouda S. Patil, Raghavendra G. Amachawadi, Rajendra Prasad S, Ghada Lamraoui, Abdulaziz A. Al-Kheraif, Abdallah M. Elgorban, Asad Syed, Chandan Shivamallu   +11 more
doaj   +1 more source

In situ, in vitro and in silico analysis of coating performance [PDF]

, 2009
Service life prediction (SLP) is a complex yet essential method for analysing coating performance. Accurate and precise assessment is crucial for a strong position on the market.
Boone, Matthieu, De Windt, Imke, Van Acker, Joris, Van den Bulcke, Jan   +3 more
core  

Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance. [PDF]

, 2012
Background and aimsThe root apical meristem (RAM) is the plant stem cell niche which provides for the formation and continuous development of the root.
Doroshkov, AV, Kazantsev, FV, Kochetov, AV, Kolchanov, NA, Likhoshvai, VA, Mironova, VV, Mjolsness, E, Novoselova, ES, Omelyanchuk, NA   +8 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Ergosterol as a natural modulator of intestinal cholesterol absorption via NPC1L1: an in silico insight into hypercholesterolemia

Frontiers in Bioinformatics
IntroductionCardiovascular disease (CVD) is the leading cause of death worldwide and is substantially caused by high cholesterol levels. High levels of low-density lipoprotein cholesterol (LDL-C) lead to atherosclerosis, which greatly raises the risk of ...
Aparna G. Shenoy, Amrithesh Sureshkumar, Vishal Ravi, Rajesh Raju, Niyas Rehman   +4 more
doaj   +1 more source