Results 31 to 40 of about 497,128 (308)
In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]
, 2010 The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg +5 more
core +5 more sources
Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals [PDF]
, 2020 Background: The HIV-1 proviral genome harbors multiple CpG islands (CpGIs), both in the promoter and intragenic regions. DNA methylation in the promoter region has been shown to be heavily involved in HIV-1 latency regulation in cultured cells.
De Meyer, Tim +7 more
core +2 more sources
IN-SILICO ANALYSIS; ANALYSIS OF S-303 BINDING TO CD-61 OF PLATELETS
THE PROFESSIONAL MEDICAL JOURNAL, 2016 ntroduction: Different pathogen reducing technologies are being implementedwhich includes S-303. CD-61 is important receptor for clotting. Pathogen reducing agents arebeing studied extensively to probe its effects. Objective: We conducted this study to reviewthe docking of S-303 at CD-61, to look into the effect of S-303 on function of platelets ...
Hammad Tufail Chaudhary, Shahida Hasnain
openaire +2 more sources
In Silico Analysis of Huntingtin Homologs in Lower Eukaryotes [PDF]
International Journal of Molecular Sciences, 2021 Huntington’s disease is a rare neurodegenerative and autosomal dominant disorder. HD is caused by a mutation in the gene coding for huntingtin (Htt). The result is the production of a mutant Htt with an abnormally long polyglutamine repeat that leads to pathological Htt aggregates.
Valentina Brandi, Fabio Polticelli
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Fluctuating Nonlinear Spring Model of Mechanical Deformation of Biological Particles [PDF]
, 2015 We present a new theory for modeling forced indentation spectral lineshapes of biological particles, which considers non-linear Hertzian deformation due to an indenter-particle physical contact and bending deformations of curved beams modeling the ...
Gijs J L Wuite +6 more
core +4 more sources
Revealing the Potential of Bioactive Peptides from Sheep Milk Casein and Whey: An In-silico Exploration [PDF]
BIO Web of ConferencesSheep casein and whey proteins, α-lactalbumin, β-lactalbumin, and β-lactoglobulin 1/B, are good sources of bioactive peptides that have potential health benefits including antimicrobial, antioxidant, antihypertensive, and immunomodulatory activities. The
K Sathika +4 more
doaj +1 more source
In Silico Analysis of the Immunological Landscape of Pituitary Adenomas
Neurosurgery, 2020 Immunotherapy has gained traction in the treatment of solid tumors but the immunological landscape of pituitary adenomas is not well defined. We sought to investigate the immunological composition in pituitary adenomas using RNA deconvolution (CIBERSORTx) on an existing gene expression dataset for pituitary adenomas.We applied an established ...
Jacky T, Yeung +2 more
openaire +3 more sources
From Single to Complex Pollutants: In-silico Tools to Decipher the Decisive Role of Basidiomycetous Fungi for Dye Transformation [PDF]
BIO Web of ConferencesThe industrial discharge of synthetic dyes from textile production and related processes creates environmental contamination because these synthetic dyes exist as complex pollutant mixtures instead of single harmful substances.
Negi Khushi, Sattiraju Krishna Sundari
doaj +1 more source
In silico analysis of Eucalyptus thioredoxins [PDF]
Genetics and Molecular Biology, 2005 The Eucalyptus Genome Sequencing Project (FORESTs), an initiative from the Brazilian ONSA consortium (Organization for Nucleotide Sequencing and Analysis), has achieved the sequencing of 123.889 EST clones from 18 different cDNA libraries. We have investigated the FORESTs data set to identify EST clusters potentially encoding thioredoxins (TRX).
Barbosa, Aulus Estevão, Marinho, Paulo
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In‐silico analysis of the strigolactone ligand‐receptor system [PDF]
Plant Direct, 2020 AbstractStrigolactones (SLs) are a diverse class of butenolide‐bearing plant hormones associated with several processes of major agricultural concern. SLs initiate symbiosis between plants and arbuscular mycorrhizal fungi, cause germination of crop‐devastating parasitic plants, and inhibit shoot branching in vascular plants.
Marco Bürger, Joanne Chory
openaire +3 more sources