Results 11 to 20 of about 497,128 (308)

Bioinformatic Resources for in Silico Proteome Analysis [PDF]

open access: yesBioMed Research International, 2003
In the growing field of proteomics, tools for the in silico analysis of proteins and even of whole proteomes are of crucial importance to make best use of the accumulating amount of data. To utilise this data for healthcare and drug development, first the characteristics of proteomes of entire species—mainly the human—have to be understood, before ...
Pruess, Manuela, Apweiler, Rolf
openaire   +2 more sources

In silico gene expression analysis – an overview [PDF]

open access: yesMolecular Cancer, 2007
Abstract Efforts aimed at deciphering the molecular basis of complex disease are underpinned by the availability of high throughput strategies for the identification of biomolecules that drive the disease process. The completion of the human genome-sequencing project, coupled to major technological developments, has afforded investigators ...
MacMathuna Padraic   +3 more
openaire   +3 more sources

The search for molecular mimicry in proteins carried by extracellular vesicles secreted by cells infected with Plasmodium falciparum

open access: yesCommunicative & Integrative Biology, 2021
Red blood cells infected with Plasmodium falciparum secrete extracellular vesicles in order to facilitate the survival and infection of human cells.
Vinicio Armijos-Jaramillo   +3 more
doaj   +1 more source

The Adapted POM Analysis of Avenanthramides In Silico

open access: yesPharmaceuticals, 2023
POM analysis and related approaches are significant tools based on calculating various physico-chemical properties and predicting biological activity, ADME parameters, and toxicity of a molecule. These methods are used to evaluate a molecule’s potential to become a drug candidate.
Tibor Maliar   +8 more
openaire   +3 more sources

The emerging role of Deubiquitinases (DUBs) in parasites: A foresight review

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Before the discovery of the proteasome complex, the lysosomes with acidic proteases and caspases in apoptotic pathways were thought to be the only pathways for the degradation of damaged, unfolded, and aged proteins. However, the discovery of 26S and 20S
Prakash Kumar   +4 more
doaj   +1 more source

Greener Synthesis, In-Silico and Theoretical Analysis of Hydrazides as Potential Antituberculosis Agents (Part 1)

open access: yesChemistry Proceedings, 2021
Since several decades, our healthcare burden has been increased due to tremendous cases of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) infections, especially in tropical countries.
Suraj N. Mali   +3 more
doaj   +1 more source

Genetic, haplotype and phylogenetic analysis of Ligula intestinalis by using mt-CO1 gene marker: ecological implications, climate change and eco-genetic diversity

open access: yesBrazilian Journal of Biology, 2022
Ligula intestinalis is a cestode parasite that affects freshwater fish in different countries of the world. The current study aims to reveal the phylogenetic, genetic and haplotype diversity of mt-CO1 gene sequences sent to the NCBI database from ...
M. A. Selcuk   +6 more
doaj   +1 more source

Review on Multiple Facets of Drug Resistance: A Rising Challenge in the 21st Century

open access: yesJournal of Xenobiotics, 2021
With the advancements of science, antibiotics have emerged as an amazing gift to the human and animal healthcare sectors for the treatment of bacterial infections and other diseases.
Mousumi Saha, Agniswar Sarkar
doaj   +1 more source

Chemical Bonding in the Boron Buckyball [PDF]

open access: yes, 2008
A symmetry analysis of the valence shell in the boron buckyball B80, shows a perfect match with the symmetry of the valence shell in C60 .The cap atoms participate in the bonding by 30 orbitals which transform as the sigma bonds along the 6-6 edges.
Ceulemans, Arnout   +3 more
core   +1 more source

In silico comparative analysis of conserved genes expressed in solanaceous plants under abiotic stresses [PDF]

open access: yes, 2011
The gene expression data was studied in order to analyze genes involved in different abiotic stresses in solanaceous plants. Salt, temperature (heat & cold) and drought are the main abiotic stresses to the plants.
ashok sharma   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy