Results 51 to 60 of about 83,691,994 (313)

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

open access: yes, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Stanyon, Roscoe   +3 more
core   +1 more source

Les documents d’architectes : des archives essentielles pour l’étude des lycées [PDF]

open access: yes, 2021
De nombreux architectes, certains jouissant d’une certaine renommée, sont intervenus depuis la fin du xixe siècle dans la conception des lycées jusqu’au milieu du xxe siècle.
Franck Delorme   +2 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Mechanism of mechanical strength degradation and microstructure evolution of anthracite induced by supercritical carbon dioxide

open access: yesMeitan kexue jishu
In order to reveal the effect of supercritical carbon dioxide on the mechanical strength and microstructure of anthracite in the process of CO2 injection into deep coal seams, takes anthracite as the research object, the degradation characteristics of ...
Yichao JIA   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Investigation into the Fracture Evolution Law of Overlying Strata Roof in Shallowly Buried “Three-Soft” Coal Seam Fully Mechanized Mining Faces and Its Influence on the Feasibility of Gob-Side Entry Retaining

open access: yesApplied Sciences
To address the feasibility of gob-side entry retaining in the shallow-buried three-soft coal seam fully mechanized mining face (SB-TSCS FMMF) of Xindeng (Zhengzhou, China) Coal Industry, we established a mechanical model of post-mining roof–coal-rock ...
Guoyou Hu   +3 more
doaj   +1 more source

Architecture and Nation. The Schleswig Example, in comparison to other European Border Regions [PDF]

open access: yes, 2019
Looking back at the five analyzed border regions, one might conclude that the relations between nation and nationality on one hand and architecture on the other hand demonstrate interesting similarities and differences.
Dragsbo, Peter, Peter Dragsbo
core   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier   +3 more
wiley   +1 more source

Study on mechanics and permeability evolution of sandy mudstone during full stress-strain loading

open access: yesMeitan xuebao
The evolution law of surrounding rock pore crack and its permeability change during soft rock roadway excavation is one of the basic scientific problems to be solved in water inrush disaster prevention and grouting reinforcement of weak surrounding rock.
Zhaoyun CHAI   +5 more
doaj   +1 more source

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