Results 51 to 60 of about 2,914,320 (305)

Physical and mechanical characterization of the soft pyroclastic rocks forming the Orvieto cliff [PDF]

, 2002
The paper describes the results of laboratory and in situ investigations carried out on weak pyroclastic materials which could be encountered during engineering activities in volcanic regions.
RIBACCHI, Renato, ROTONDA, Tatiana, TOMMASI P   +2 more
core  

Rescue Path Planning and Simulation Analysis of Mining Robot Based on Improved A* Algorithm

Taiyuan Ligong Daxue xuebao
Purposes The situation of post-disaster site of coal mine underground is complex. Aiming at the fact that traditional A* algorithm-based coal mine robot rescue path planning bears path insecurity, low efficiency, and other problems, and by combining with
Biying DUAN, Zhaoyun CHAI, Zipeng XIN, Ke YAN, Chang XIAO, Xiangyu LIU, Tianyu LI, Xinyu LIU   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Superconducting MgB2 thin films by pulsed laser deposition [PDF]

, 2001
Growth of MgB2 thin films by pulsed laser deposition is examined under ex situ and in situ processing conditions. For the ex situ process, Boron films grown by PLD were annealed at 900 C with excess Mg.
C. Petrovic, Finnemore D. K., G. Lapertot, P. C. Canfield, R. L. Greene, S. B. Ogale, S. L. Bud’ko, S. R. Shinde, T. Venkatesan   +8 more
core   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Mechanism of mechanical strength degradation and microstructure evolution of anthracite induced by supercritical carbon dioxide

Meitan kexue jishu
In order to reveal the effect of supercritical carbon dioxide on the mechanical strength and microstructure of anthracite in the process of CO2 injection into deep coal seams, takes anthracite as the research object, the degradation characteristics of ...
Yichao JIA, Dong YANG, Xudong HUANG, Dingwei SUN, Liguo HE   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Accreted versus In Situ Milky Way Globular Clusters [PDF]

, 2010
Here we examine the Milky Way's GC system to estimate the fraction of accreted versus in situ formed GCs. We first assemble a high quality database of ages and metallicities for 93 Milky Way GCs from literature deep colour-magnitude data.
Abadi, Allen, Allen, Bekki, Bekki, Bekki, Bellazzini, Bellazzini, Bellazzini, Bellazzini, Bellazzini, Bullock, Burkert, Carollo, Carraro, Carraro, Carraro, Carrera, Carrera, Carretta, Catelan, Coleman, Côté, de Angeli, Dinescu, Dinescu, Dinescu, Dotter, Dotter, Duffau, Duncan A. Forbes, Durrell, Fellhauer, Font, Forbes, Forbes, Frinchaboy, Fusi Pecci, Glatt, Grillmair, Harris, Helmi, Helmi, Helmi, Ibata, Koposov, Lanfranchi, Lauchner, Law, Layden, Lee, Lee, Lin, Lynden-Bell, Mackey, Mackey, Mackey, Martin, Marín-Franch, Mateu, Mayer, Mayer, McConnachie, Minniti, Newberg, Newberg, Norris, Peñarrubia, Peñarrubia, Piotto, Pritzl, Salaris, Searle, Siegel, Spitler, Terry Bridges, Unavane, van den Bergh, van den Bergh, Willett, Zolotov   +80 more
core   +1 more source

Investigation into the Fracture Evolution Law of Overlying Strata Roof in Shallowly Buried “Three-Soft” Coal Seam Fully Mechanized Mining Faces and Its Influence on the Feasibility of Gob-Side Entry Retaining

Applied Sciences
To address the feasibility of gob-side entry retaining in the shallow-buried three-soft coal seam fully mechanized mining face (SB-TSCS FMMF) of Xindeng (Zhengzhou, China) Coal Industry, we established a mechanical model of post-mining roof–coal-rock ...
Guoyou Hu, Yongkang Yang, Shuai Li, Konghao Zhu   +3 more
doaj   +1 more source