Results 131 to 140 of about 115,013,792 (297)

Farmers' Use of Improved Seed Selection Practices in Mexican Maize: Evidence and Issues from the Sierra de Santa Marta [PDF]

open access: yes
The principal advantage of in situ conservation is that it allows adaptive evolutionary processes to continue in the species that are being conserved. For a cultivated crop species, in situ conservation involves farmers' management of their own genetic ...
Blanco, Jose-Luis   +2 more
core  

A Universal Protein Ladder for Standardization of Diverse FRET Assays

open access: yesAdvanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith   +5 more
wiley   +1 more source

Uprooting Diversity? Peasant Farmers’ Market Engagements and the on-Farm Conservation of Crop Genetic Resources in the Guatemalan Highlands [PDF]

open access: yes
The long-term security of the global food supply is contingent upon the on-farm conservation of crop genetic diversity. Without it, food crops lack the ability to evolve in the face of new pests, emerging plant diseases, and changing environmental ...
S. Ryan Isakson
core  

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang   +22 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Computing Opportunity Costs of Growing Local Varieties for On-farm Conservation: Illustrations Using Sorghum Data from Ethiopia [PDF]

open access: yes
The recent shift of emphasis to on-farm conservation is driven by its diverse attractive features - participatory nature, dynamic nature, capacity to maintain not only crop diversity but the knowledge that evolves with it, the chance it offers and the ...
Mburu, John G.   +2 more
core  

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

open access: yesAdvanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma   +10 more
wiley   +1 more source

VARIETY CHARACTERISTICS AND THE LAND ALLOCATION DECISIONS OF FARMERS IN A CENTER OF MAIZE DIVERSITY [PDF]

open access: yes
There is emerging interest in the prospects for enhancing farmers' management of genetic resources as a complementary strategy to ex situ conservation.
Aguirre, Alfonso   +2 more
core  

Other title: Publications issued by the Kansas State Conservation Commission and the Division of Conservation, Kansas Department of Agriculture, 2000-2011

open access: yes, 2000
application/pdfA set of four publications gathered from the Kansas Division of Conservation and Kansas State Conservation Commission websites.Make Learning Fun: Conservation Education (2000) Watershed District Handbook (2008) Kansas Conservation District
Kansas. State Conservation Commission.
core   +1 more source

IN SITU AND EX SITU CONSERVATION IN BIODIVERSITY PROTECTION

open access: yes
Conservation of biodiversity is essential for maintaining the ecological balance, ensuring sustainable ecosystems, and supporting human livelihoods. It requires strategies that protect species, populations, and habitats from extinction, genetic erosion, and environmental degradation.
openaire   +2 more sources

Home - About - Disclaimer - Privacy