Results 21 to 30 of about 193,895 (260)
Nanoparticles laden in situ gelling system for ocular drug targeting
Journal of Advanced Pharmaceutical Technology & Research, 2013 Designing an ophthalmic drug delivery system is one of the most difficult challenges for the researchers. The anatomy and physiology of eye create barriers like blinking which leads to the poor retention time and penetration of drug moiety.
Divya Kumar +3 more
doaj +1 more source
Indian Journal of Pharmaceutical and Biological Research, 2016 Oral route is technique which is used over a decades. It is most preferred and common technique for oral administration of drug in the body, but due to certain limitation such as absorption of drug, drug targeting to particular organ can cause problem for administration through oral route.
Preeti Kothiyal +3 more
openaire +1 more source
Nanoparticles laden in situ gel for sustained ocular drug delivery
Journal of Pharmacy and Bioallied Sciences, 2013 Proper availability of drug on to corneal surface is a challenging task. However, due to ocular physiological barriers, conventional eye drops display poor ocular bioavailability of drugs (< 1%).
Himanshu Gupta +5 more
doaj +1 more source
Formulation and evaluation of periodontal in situ gel
International Journal of Pharmaceutical Investigation, 2013 The present study was aimed to develop and optimize in situ gel for the treatment of periodontal disease.Temperature-sensitive in situ gel containing 0.1% w/v Chlorhexidine hydrochloride was formulated by cold method using different polymers. Preliminary study was carried out to optimize different types and concentration of polymers such as Poloxamer ...
Garala, Kevin +4 more
openaire +3 more sources
Pharmaceuticals, 2023 Brimonidine tartrate (BRT) is a highly selective α2 adrenergic receptor agonist as treatment for patients with open angle glaucoma and high intraocular pressure.
Haonan Xu +6 more
doaj +1 more source
Development and evaluation of in situ gel of pregabalin
International Journal of Pharmaceutical Investigation, 2015 Pregabalin (PRG), an analog of gamma-aminobutyric acid, reduces the release of many neurotransmitters, including glutamate, and noradrenaline. It is used for the treatment of epilepsy; simple and complex partial convulsion. The present research work aims to ensure a high drug absorption by retarding the advancement of PRG formulation through the ...
Madan, Jyotsana R. +2 more
openaire +3 more sources
Lime Peel Oil–Incorporated Rosin-Based Antimicrobial In Situ Forming Gel
Gels, 2022 Localized intra-periodontal pocket drug delivery using an injectable in situ forming gel is an effective periodontitis treatment. The aqueous insoluble property of rosin is suitable for preparing a solvent exchange-induced in situ forming gel. This study
Ei Mon Khaing +3 more
doaj +1 more source
Nanoemulsion-based nasal in situ gel of olanzapine.
Journal of Excipients and Food Chemicals, 2023 Oral delivery of olanzapine suffers from low oral bioavailability and there has been reports of metabolic side effects. This study aimed to prepare a nanoemulsion of olanzapine and incorporate it into an in situ gel for nasal delivery.
Zahraa H Ali, Myasar Alkotaji
doaj
Temperature-dependent in Situ Gel of Clotrimazole: an Experimental Study
Folia Medica, 2019 Background: The in-situ gel-forming polymeric formulations offer sustained and prolonged action in comparison to conventional drug delivery systems.
Patel Vipul P. +3 more
doaj +1 more source
Controlled ocular drug delivery of ofloxacin using temperature modulated in situ gelling system
Journal of the Scientific Society, 2013 Background: The designing of ocular dosage form off ers complicated issues. Numerous protective mechanisms are present in the eye to prevent the absorption of drug candidate from the corneal membrane.
Upendra Nagaich +3 more
doaj +1 more source