Applied Sciences, 2022 Finite element (FE) analyses contribute to a better understanding of the human lumbar spine’s biomechanics and serve as an effective predictive tool.
Mate Turbucz +6 more
doaj +1 more source
Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. [PDF]
, 2020 Genetic variants are the primary driver of congenital heart disease (CHD) pathogenesis. However, our ability to identify causative variants is limited.
Bernstein, Daniel +25 more
core
2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador [PDF]
, 2017 Background: Rhodnius ecuadoriensis is the main triatomine vector of Chagas disease, American trypanosomiasis, in Southern Ecuador and Northern Peru.
Andersson, Björn +10 more
core +4 more sources
Sleep Spindles as an Electrographic Element: Description and Automatic Detection Methods
Neural Plasticity, 2016 Sleep spindle is a peculiar oscillatory brain pattern which has been associated with a number of sleep (isolation from exteroceptive stimuli, memory consolidation) and individual characteristics (intellectual quotient).
Dorothée Coppieters ’t Wallant +2 more
doaj +1 more source
AN EXAMPLE OF TEMPLATE BASED PROTEIN STRUCTURE MODELING BY GLOBAL OPTIMIZATION
TASK Quarterly, 2016 CASP (Critical Assessment of protein Structure Prediction) is a community-wide experiment for protein structure prediction taking place every two years since 1994.
KEEHYOUNG JOO, INSUK JOUNG, JOOYOUNG LEE
doaj +1 more source
In silico toxicology protocols
Regulatory Toxicology and Pharmacology, 2018 The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It highlights the need to develop standardized protocols when conducting toxicity-related predictions.
Myatt, Glenn J. +83 more
openaire +3 more sources
Truly Target-Focused Pharmacophore Modeling: A Novel Tool for Mapping Intermolecular Surfaces
Molecules, 2018 Pharmacophore models are an accurate and minimal tridimensional abstraction of intermolecular interactions between chemical structures, usually derived from a group of molecules or from a ligand-target complex.
Jérémie Mortier +2 more
doaj +1 more source
A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]
, 2010 Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex +95 more
core +6 more sources
Desain Primer Secara in Silico Untuk Amplifikasi Fragmen Gen Rpob Mycobacterium Tuberculosis Dengan Polymerase Chain Reaction (Pcr) [PDF]
, 2013 Amplifikasi DNA Mycobacterium tuberculosis dari gen rpoB dilakukan dengan metode polymerase chain reaction (PCR). Amplifikasi DNA dengan PCR diperlukan sepasang primer (forward dan reverse) untuk membatasi daerah yang ingin diamplifikasi.
C, Y. S. (Yowani) +2 more
core
, 2007 We have extended our previously developed 3D multi-scale agent-based brain tumor model to simulate cancer heterogeneity and to analyze its impact across the scales of interest.
Deisboeck, Thomas S. +3 more
core +1 more source