Results 161 to 170 of about 70,838 (262)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Ex Situ Conservation, DNA Barcoding and Enzymatic Potential Evaluation of Macrofungi (Basidiomycota, Ascomycota) from Vietnam. [PDF]

J Fungi (Basel)
Psurtseva NV, Kiyashko AA, Senik SV, Pham THG.   +3 more
europepmc   +1 more source

Drying banana seeds for ex situ conservation. [PDF]

Conserv Physiol, 2022
Kallow S, Garcia Zuluaga M, Fanega Sleziak N, Nugraha B, Mertens A, Janssens SB, Gueco L, Valle-Descalsota ML, Dang Vu T, Toan Vu D, Thi Li L, Vandelook F, Dickie JB, Verboven P, Swennen R, Panis B.   +15 more
europepmc   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Potential of Ex Situ Conservation Strains Revealed by Genetic Analysis of Oceanic Islands' Endangered Species Pittosporum parvifolium. [PDF]

Ecol Evol
Kawakita H, Sakaguchi S, Katoh S, Kato H, Tanaka T, Komaki Y, Ideno T, Setoguchi H.   +7 more
europepmc   +1 more source

Strong restructuration of skin microbiota during captivity challenges ex-situ conservation of amphibians. [PDF]

Front Microbiol, 2023
Fieschi-Méric L, Van Leeuwen P, Hopkins K, Bournonville M, Denoël M, Lesbarrères D.   +5 more
europepmc   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Linking Gut Microbiota and Stereotypic Behavior of Endangered Species Under Ex Situ Conservation: First Evidence from Sun Bears. [PDF]

Animals (Basel)
Chen X, Chen W, Guo X, Zhang S, Xu B, Wu H, Zhao D.   +6 more
europepmc   +1 more source

Corrigendum to: Drying banana seeds for ex situ conservation. [PDF]

Conserv Physiol, 2022
Kallow S, Garcia Zuluaga M, Fanega Sleziak N, Nugraha B, Mertens A, Janssens SB, Gueco L, Valle-Descalsota ML, Dang Vu T, Toan Vu D, Thi Le L, Vandelook F, Dickie JB, Verboven P, Swennen R, Panis B.   +15 more
europepmc   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source