Results 151 to 160 of about 384,374 (305)

Long-Term In Situ Conservation Drove Microevolution of Solina d'Abruzzo Wheat on Adaptive, Agronomic and Qualitative Traits. [PDF]

Plants (Basel), 2023
Morcia C, De Flaviis R, Terzi V, Gasparelli ME, Ghizzoni R, Badeck FW, Rizza F, Santarelli V, Tumino G, Sacchetti G.   +9 more
europepmc   +1 more source

In situ conservation: The Ethiopian experience [PDF]

Plant species of economic importance are not randomly distributed throughout the world. Ethiopia has considerable plant genetic diversity because it has a wide range of eco-geographic, edaphic and climatic conditions.

core  

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Cryo-Technologies for Ex Situ Conservation of Rosa Germplasm. [PDF]

Plants (Basel), 2022
Halmagyi A, Vălimăreanu S, Șovărel G, Coste A.   +3 more
europepmc   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

State of ex situ conservation of landrace groups of 25 major crops. [PDF]

Nat Plants, 2022
Ramirez-Villegas J, Khoury CK, Achicanoy HA, Diaz MV, Mendez AC, Sosa CC, Kehel Z, Guarino L, Abberton M, Aunario J, Awar BA, Alarcon JC, Amri A, Anglin NL, Azevedo V, Aziz K, Capilit GL, Chavez O, Chebotarov D, Costich DE, Debouck DG, Ellis D, Falalou H, Fiu A, Ghanem ME, Giovannini P, Goungoulou AJ, Gueye B, Hobyb AE, Jamnadass R, Jones CS, Kpeki B, Lee JS, McNally KL, Muchugi A, Ndjiondjop MN, Oyatomi O, Payne TS, Ramachandran S, Rossel G, Roux N, Ruas M, Sansaloni C, Sardos J, Setiyono TD, Tchamba M, van den Houwe I, Velazquez JA, Venuprasad R, Wenzl P, Yazbek M, Zavala C.   +51 more
europepmc   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Age Structure, Development and Population Viability of Banteng (Bos javanicus) in Captive Breeding for Ex-Situ Conservation and Reintroduction. [PDF]

Animals (Basel), 2023
Chaiyarat R, Sriphonkrang N, Khamsirinan P, Nakbun S, Youngpoy N.   +4 more
europepmc   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Natural Ageing-Related Alterations of Biological Markers in Maize Seeds Under Ex-Situ Conservation. [PDF]

Int J Mol Sci
Kravic N, Zilic S, Vukadinovic J, Petrovic T, Milivojevic M, Srdic J, Simic M, Mladenovic Drinic S, Andjelkovic V.   +8 more
europepmc   +1 more source