Results 141 to 150 of about 70,838 (262)

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source

In Situ Conservation of Orchidaceae Diversity in the Intercontinental Biosphere Reserve of the Mediterranean (Moroccan Part). [PDF]

Plants (Basel)
El Karmoudi Y, Krigas N, Chergui El Hemiani B, Khabbach A, Libiad M.   +4 more
europepmc   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

Genetic diversity analysis and conservation strategy recommendations for ex situ conservation of Cupressus chengiana. [PDF]

BMC Plant Biol
Chen C, Chang H, Pang X, Liu Q, Xue L, Yin C.   +5 more
europepmc   +1 more source

Morphological variability of wild-growing crown imperial (Fritillaria imperialis L.) germplasm in central region of Iran-implications for in-situ conservation initiatives. [PDF]

BMC Plant Biol, 2023
Moradi M, Khaleghi A, Khadivi A.
europepmc   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Effects of ex situ conservation on commensal bacteria of crocodile lizard and conservation implications. [PDF]

Vet Q
Jiang H, Lv M, He T, Xie M, Zhao Z, He J, Luo S, Guo Y, Chen J.   +8 more
europepmc   +1 more source

In situ conservation of traditional vegetable diversity in Wa homegardens in southwestern Yunnan, China. [PDF]

J Ethnobiol Ethnomed, 2021
Shao H, Hill R, Xue D, Yang J.
europepmc   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

Tuberculosis Susceptibility and Inbreeding Depression Hinder <i>Ex Situ</i> Conservation in a Critically Endangered Rainforest Bird. [PDF]

Evol Appl
Bolton PE, Foote DJ, Drilling NE, McRae SB, Sorenson MD, Balakrishnan CN.   +5 more
europepmc   +1 more source