Results 81 to 90 of about 193,900 (263)

Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation

Frontiers in Pharmacology
Introduction: Escitalopram oxalate (ESCI) is a biopharmaceutical classification system (BCS) class II antidepressant drug, that suffers limited oral bioavailability due to extensive hepatic metabolism.
Md Ali Mujtaba, Md Ali Mujtaba, Md Abdur Rashid, Mangesh D. Godbole, Yahya Alhamhoom, Divyashri S. Shende, Sameer Alshehri, Mohammad J. Akbar, Mohammed Kaleem, Ujwala N. Mahajan, Naiyer Shahzad   +10 more
doaj   +1 more source

pH-Inducedin situgel for periodontal anesthesia

Indian Journal of Pharmaceutical Sciences, 2008
A pH mediated in situ gelling system was developed using prilocaine hydrochloride for periodontal anesthesia using combination of chitosan and hydroxypropylmethylcellulose. The gel so developed can be used as anaesthetic in lengthy dental surgery. The gel was evaluated for many parameters like gelation pH, viscosity, physicochemical properties, in ...
Gupta, H., Singh, R. M., Singh, G. N., Kaushik, D., Sharma, A.   +4 more
openaire   +3 more sources

Structural Power Composites Based on High Mass Loading Zn‐Ion Hybrid Supercapacitors with Metal Mesh Current Collectors and Aramid Nanofiber/Glass Fiber Composite Electrolytes

Advanced Functional Materials, EarlyView.
A multifunctional structural power composite is developed by integrating high‐mass‐loading Zn‐ion hybrid supercapacitors with metal mesh current collectors and aramid nanofiber‐based composite electrolytes, enabling simultaneous load‐bearing capability and enhanced areal energy storage.
Yuseung Choi, Gilyong Shin, Hoyeon Lee, Eun Jae Nam, Byeong Jun So, Sungryul Yun, Fu‐Kuo Chang, Jei Gyeong Jeon, Tae June Kang   +8 more
wiley   +1 more source

Tannic Acid‐Modified Cellulose Nanofiber Reinforced Polymerizable Eutectogels for High‐Performance Stretchable Strain Sensors

Advanced Functional Materials, EarlyView.
A polymerizable deep eutectic solvent is reinforced with tannic acid‐modified cellulose nanofibers to construct a hierarchical dynamic eutectogel network. Synergistic covalent and reversible interactions impart ultrahigh stretchability, high ionic conductivity, broad temperature tolerance, self‐healing, and strong adhesion, enabling robust wearable ...
Huang Wu, Yang Hu, Youmin Tuo, Weide Zhang, Nanzhu Bao, Haitao Wu, Zhuangzhuang Chu, Yunhua Chen, Tao Wang, Teng Yuan, Hongbo Zeng, Zhuohong Yang   +11 more
wiley   +1 more source

Reconstructing Quantum Dot Surfaces via Dual‐Functional Ligand Pairing Enables Efficient Shortwave Infrared Optoelectronics

Advanced Functional Materials, EarlyView.
This work presents a ligand‐pairing strategy that reconstructs lead sulfide quantum dot surfaces for efficient short‐wave infrared optoelectronics. A low‐reactivity thiourea precursor combined with hydrobromic acid enables monodisperse and fully passivated quantum dots.
Dongeon Kim, Minjung Yang, Yunjin Lee, Gaeun Cho, Min‐Jae Si, Jaewoo Jeong, Seoryeon Jeong, Sol‐Hee Kim, Taeho Han, Seungin Jee, Byeong‐Chan Kim, Woong Kim, Seungmin Lee, Jun Hong Noh, Han Seul Kim, Yujin Jung, Se‐Woong Baek   +16 more
wiley   +1 more source

Doxorubicin-loaded zein in situ gel for interstitial chemotherapy of colorectal cancer

Acta Pharmaceutica Sinica B, 2012
The aim of this research was to evaluate doxorubicin (DOX)-loaded zein in situ gels, a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection.
Ning Shen, Jie Hu, Linan Zhang, Li Zhang, Yongjun Sun, Yinghua Xie, Shaomei Wu, Lei Liu, Zibin Gao   +8 more
doaj   +1 more source

Bridging Polymer Brushes and Coatings Through Ultra‐Thick Growth by Surface‐Initiated Photoiniferter Polymerization

Advanced Functional Materials, EarlyView.
Surface‐initiated photoiniferter‐mediated polymerization (SI‐PIMP) enables the controlled growth of UHMW polymer brushes with multi‐micrometer thicknesses, bridging conventional brushes and bulk‐like coatings. UHMW brushes are synthesized through a controlled/living process; they provide low friction and enhanced wear resistance under aqueous ...
Elena Avanzini, Emanuele Grigolon, Lily E. Diodati, Matteo Savio, Megan E. Lott, Kaden C. Stevens, Francesca Lorandi, Brent S. Sumerlin, Edmondo M. Benetti   +8 more
wiley   +1 more source

Effectiveness and safety of 0.15% ganciclovir in situ ophthalmic gel for herpes simplex keratitis – a multicenter, randomized, investigator-masked, parallel group study in Chinese patients

Drug Design, Development and Therapy, 2013
Tong Lin,1 Lan Gong,1 Xing-huai Sun,1 Nai-qing Zhao,2 Wei Chen,3 Hui-ping Yuan,4 Yan Shao,5 Ming-hong Gao,6 Hai Tang71Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, People’s Republic of China; 2Department of ...
Lin T, Gong L, Sun XH, Zhao NQ, Chen W, Yuan HP, Shao Y, Gao MH, Tang H   +8 more
doaj  

Tough and Skin‐Free Porous Polyelectrolyte Complex Hydrogels via Salt‐Induced Aqueous Phase Separation

Advanced Functional Materials, EarlyView.
Controlling counterion exchange rate during aqueous phase separation enables the formation of skin‐free, homogeneously porous polyelectrolyte complex hydrogels by suppressing kinetically trapped skin layers and macrovoids. The resulting hydrogel networks exhibit exceptional toughness (∼15 MJ·m−3) and enable 3D (bio)printing and post‐functionalization ...
Adrivit Mukherjee, Vishakha Vishakha, Julien Es Sayed, Hugo Brummer, Peter Dijkstra, Ajay Giri Prakash Kottapalli, Ranjita K. Bose, Marleen Kamperman   +7 more
wiley   +1 more source

Preparation and Characterization of Tacrolimus-Loaded SLNs in situ Gel for Ocular Drug Delivery for the Treatment of Immune Conjunctivitis

Drug Design, Development and Therapy, 2021
Kexin Sun, Ke Hu Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, People’s Republic of ChinaCorrespondence: Ke Hu Email ...
Sun K, Hu K
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