Results 41 to 50 of about 2,801,410 (319)

Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries [PDF]

, 1993
The nuclear topography of splicing snRNPs, mRNA transcripts and chromosome domains in various mammalian cell types are described. The visualization of splicing snRNPs, defined by the Sm antigen, and coiled bodies, revealed distinctly different ...
A Monneron, A Schneider-G�dicke, AK Raap, B Roggenbuck, C Benyajati, C Collins, C Cremer, C Zorn, CA Ascoli, D Pinkel, D Pinkel, DE Comings, DJ Arndt-Jovin, DL Spector, DL Spector, DL Spector, DL Spector, DL Spector, DM Shotton, EA Lerner, G Blobel, GJ Brakenhoff, HTM Voort Van der, I Raska, J Bradl, JB Lawrence, JD Northway, JG Gall, JR Paulson, KC Carter, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, LEC Andrade, M Bachmann, M Bouteille, M Carmo-Fonseca, M Carmo-Fonseca, M Carmo-Fonseca, M Carmo-Fonseca, M Hochstrasser, M Mattioli, M Schardin, N Hutchison, P Lichter, P Lichter, P Lichter, P Lichter, R Berezney, R Reuter, R Verheijen, S Fakan, S Fakan, S Huang, SA Berman, T Cremer, T Cremer, TM Jovin, U Bond, U Nyman, Y Hiraoka, y Ramon, Y Xing, Y Xing   +64 more
core   +1 more source

Biological implications of deletion p53 by fluorescence in situ hybridization in multiple myeloma

Biomedical and Biotechnology Research Journal, 2022
Background: Multiple myeloma (MM) is a clonal plasma cell disorder characterized by heterogeneous complex genetic abnormalities. Due to the low proliferative index of plasma cells, conventional cytogenetic (CC) analysis is hampered in MM.
Vijith Vittal Shetty, Meenakshi Arumugam, Reshma Arun Shetty, Akanksha Ashok Kalal, Nagaraj Venkatesh Kulkarni, Deyyenthody Prashanth Shetty   +5 more
doaj   +1 more source

A Technical Note on Quantum Dots for Multi-Color Fluorescence in situ Hybridization [PDF]

, 2009
Quantum dots (Qdots) are semiconductor nanocrystals, which are photo-stable, show bright fluorescence with narrow, symmetric emission spectra and are available in multiple resolvable colors.
Cremer, M., Cremer, T., Grasser, F., Müller, Stefan, Neusser, M.   +4 more
core   +1 more source

Translocation (8;21) in acute nonlymphocytic leukemia delineated by chromosomal in situ suppression hybridization [PDF]

, 1991
In situ suppression hybridization with recombinant bacteriophage DNA libraries for chromosomes 8 and 21 was performed in two cases of acute nonlymphocytic leukemia, type FAB M2.
Anna Jauch, Barbara Smialek, Cremer, Cremer, Dauwerse, Fuscoe, ISCN, ISCN, Jauch, Jing Ying Qiu, Kievits, Landegent, Lichter, Lichter, Lichter, Lichter, Lux, Pinkel, Pinkel, Reinhard Becher, Ried, Susanne Popp, Thomas Cremer, Wada   +23 more
core   +1 more source

Autofluorescence correction for fluorescence in situ hybridization [PDF]

Cytometry, 1995
AbstractOptimal sensitivity of fluorescence in situ hybridization (FISH) requires bright signals and low background fluorescence. Use of locus‐specific probes is especially dependent on high sensitivity. Some tissue preparations show high autofluorescence, masking small or dim signals.
Szöllősi, János, Lockett, Steven J., Balázs, Margit, Waldman, Frederick   +3 more
openaire   +3 more sources

A modified protocol for the detection of three different mRNAs with a new-generation in situ hybridization chain reaction on frozen sections [PDF]

, 2016
A new multiple fluorescence in situ hybridization method based on hybridization chain reaction was recently reported, enabling simultaneous mapping of multiple target mRNAs within intact zebrafish and mouse embryos.
Burnstock, G, He, C, Knight, GE, Li, X, Sui, QQ, Xiang, Z, Yuan, H, Zhu, J   +7 more
core  

Chromosomal in situ suppression hybridization of human gonosomes and autosomes and its use in clinical cytogenetics [PDF]

, 1990
DNA libraries from sorted human gonosomes were used selectively to stain the X and Y chromosomes in normal and aberrant cultured human cells by chromosomal in situ suppression (CISS-) hybridization.
Cremer, Thomas, Daumer, C., Jauch, Anna, Lichter, Peter, Murken, J., Schroeder-Kurth, T.   +5 more
core   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Rapid micro fluorescence in situ hybridization in tissue sections [PDF]

, 2018
This paper describes a micro fluorescence in situ hybridization ({\mu}FISH)-based rapid detection of cytogenetic biomarkers on formalin-fixed paraffin embedded (FFPE) tissue sections. We demonstrated this method in the context of detecting human epidermal growth factor 2 (HER2) in breast tissue sections.
arxiv   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source