Significance and Regional Dependency of Peptide Transporter (PEPT) 1 in the Intestinal Permeability of Glycylsarcosine: In Situ Single-Pass Perfusion Studies in Wild-Type andPept1Knockout Mice [PDF]
Dilara Jappar+3 more
openalex +1 more source
Role and Relevance of PEPT1 in Intestinal Absorption and Pharmacokinetics of 5-Aminolevulinic Acid. [PDF]
Peptide transporter 1 (PepT1), a member of the proton-coupled oligopeptide transporter family, is known to transport di-/tri-peptides and peptidomimetics across biological membranes.
Xie, Yehua
core
Zaijin Teng,1,* Miao Yu,1,* Yang Ding,1,* Huaqing Zhang,1 Yan Shen,1 Menglao Jiang,1 Peixin Liu,1 Yaw Opoku-Damoah,2 Thomas J Webster,3 Jianping Zhou1 1Department of Pharmaceutics, State Key Laboratory of Natural Medicines, China Pharmaceutical ...
Teng Z+9 more
doaj
Evaluation of permeability and bioavailability of a lead antileishmanial compound buparvaquone in animal models [RS1-441]. [PDF]
Leishmaniasis merupakan suatu kumpulan penyakit parasit yang disebabkan oleh genus Leishmania yang kini adalah endemik di lapan puluh lapan negara. Leishmaniasis is a group of parasitic disease caused by the protozoan parasites of the genus Leishmania
Gantala Venkatesh, Gantala Venkatesh
core
Organ transplantation--then and now. [PDF]
The last 25 years have seen amazing progress in transplantation--from the development of techniques for immunosuppression to methods for organ removal and preservation.
Makowka, L, Starzl, TE
core
Reconstructing Quantitative Cerebral Perfusion Images Directly From Measured Sinogram Data Acquired Using C-arm Cone-Beam CT [PDF]
To shorten the door-to-puncture time for better treating patients with acute ischemic stroke, it is highly desired to obtain quantitative cerebral perfusion images using C-arm cone-beam computed tomography (CBCT) equipped in the interventional suite.
arxiv
P-glycoprotein (P-gp) is a trans-membrane drug efflux pump. Several drugs are P-gp substrates. Some drugs may affect the activity of P-gp by inhibiting its function, resulting in significant drug-drug interactions (DDIs).
Mehran Mesgari Abbasi+3 more
doaj
Framework to generate perfusion map from CT and CTA images in patients with acute ischemic stroke: A longitudinal and cross-sectional study [PDF]
Stroke is a leading cause of disability and death. Effective treatment decisions require early and informative vascular imaging. 4D perfusion imaging is ideal but rarely available within the first hour after stroke, whereas plain CT and CTA usually are.
arxiv
Deep generative computed perfusion-deficit mapping of ischaemic stroke [PDF]
Focal deficits in ischaemic stroke result from impaired perfusion downstream of a critical vascular occlusion. While parenchymal lesions are traditionally used to predict clinical deficits, the underlying pattern of disrupted perfusion provides information upstream of the lesion, potentially yielding earlier predictive and localizing signals.
arxiv