In this paper, as an active ingredient, puerarin chitosan nanoparticles (Pur-CS/TPP-NPs) are prepared by an ionic gelation method. The chitosan (CS) concentration, pH of the CS solution, sodium tripolyphosphate (TPP) concentration, stirring speed ...
Jie Yan+8 more
doaj +1 more source
Computer-assisted ex vivo, normothermic small bowel perfusion [PDF]
Background: In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena.
Eder, M.+6 more
core +1 more source
Baicalin Enhanced Oral Bioavailability of Sorafenib in Rats by Inducing Intestine Absorption
Background: Sorafenib (SOR) is an oral, potent, selective, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used as the first-line therapy for advanced hepatocellular carcinoma (HCC).
Jingyao Wei+13 more
doaj +1 more source
Glucose Does Not Facilitate the Absorption of Sorbitol Perfused In Situ in the Human Small Intestine , [PDF]
Sorbitol is better absorbed in the small intestine when ingested concomitantly with glucose. The aim of this study was to test in situ the effect of glucose on the absorption of sorbitol in the human small intestine, using the perfusion technique. The sorbitol absorption of three test solutions, perfused in a random order, was measured in a 30-cm ...
Laurent Beaugerie+5 more
openaire +3 more sources
Perfusion assessment via local remote photoplethysmography (rPPG) [PDF]
This paper presents an approach to assess the perfusion of visible human tissue from RGB video files. We propose metrics derived from remote photoplethysmography (rPPG) signals to detect whether a tissue is adequately supplied with blood. The perfusion analysis is done in three different scales, offering a flexible approach for different applications ...
arxiv +1 more source
Intestinal blood flow in patients with chronic heart failure: A link with bacterial growth, gastrointestinal symptoms, and cachexia [PDF]
Background: Blood flow in the intestinal arteries is reduced in patients with stable heart failure (HF) and relates to gastrointestinal (GI) symptoms and cardiac cachexia.
Alastair Watson+37 more
core +1 more source
The Effects of Cetirizine on P-glycoprotein Expression and Function In vitro and In situ [PDF]
Purpose: P-glycoprotein (P-gp) plays a major role in oral absorption of drugs. Induction or inhibition of P-gp by drugs contributes to variability of its transport activity and often results in clinically relevant drug-drug interactions.
Mehran Mesgari Abbasi+4 more
doaj +1 more source
Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion [PDF]
Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected.
Graham, V.+8 more
core +1 more source
The Effect of Particle Size on the Absorption of Cyclosporin A Nanosuspensions
Wenjun Sun,1 Jing Gao,1 Ranran Fan,2 Ting Zhang,3 Yang Tian,1 Zengming Wang,1 Hui Zhang,1 Aiping Zheng1 1Department of Pharmaceutics, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, People’s Republic of China ...
Sun W+7 more
doaj
An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat [PDF]
In the absence of an ability to absorb fluid by cellular uptake mechanisms, fluid movement in vivo from the perfused rat intestine is absorptive when the diastolic blood pressure is normal or very low but is secretory when blood pressure falls below ...
Lucas, Michael, Morrison, James
core +1 more source