Results 1 to 10 of about 7,775,334 (357)

Suspended hydrogel culture as a method to scale up intestinal organoids

open access: yesScientific Reports, 2023
Primary tissue-derived epithelial organoids are a physiologically relevant in vitro intestinal model that have been implemented for both basic research and drug development applications.
Julia Y. Co   +3 more
doaj   +1 more source

Characterization of highly expressed novel hub genes in hepatitis E virus chronicity in rabbits: a bioinformatics and experimental analysis

open access: yesBMC Veterinary Research, 2022
Background Hepatitis E virus (HEV), which is the leading cause of acute viral hepatitis worldwide, usually causes self-limited infections in common individuals. However, it can lead to chronic infection in immunocompromised individuals and its mechanisms
Manyu Li   +4 more
doaj   +1 more source

Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice

open access: yesReproductive Medicine and Biology, 2022
Background The protein proAKAP4 is crucial for sperm motility and has been suggested as an indicator of male fertility. We determined the relationship between proAKAP4 concentration and sperm motility parameters in mice, and investigated the effects of ...
Auke Boersma   +8 more
doaj   +1 more source

Comparison of immediate versus delayed frozen embryo transfer on reproductive outcome

open access: yesClinical and Experimental Obstetrics & Gynecology, 2021
The aim of this study was to compare impact of immediate versus delayed frozen frozen embryo transfer on reproductive outcome in patients undergoing IVF treatment.
Arzu Yurci   +3 more
doaj   +1 more source

Investigation of genotype diversity of 7,804 norovirus sequences in humans and animals of China

open access: yesOpen Life Sciences, 2022
Norovirus is a prominent enteric virus responsible for severe acute gastroenteritis disease burden worldwide. In our current study, we analyzed 7,804 norovirus sequences of human and animals in China which were detected from 1980 to 2020 from GenBank ...
Li Manyu   +5 more
doaj   +1 more source

Care pathway and prioritization of rapid testing for COVID-19 in UK hospitals: a qualitative evaluation

open access: yesBMC Health Services Research, 2021
Objectives The second wave of the coronavirus pandemic is now established, occurring at a time of winter pressure on acute care in the NHS. This is likely to be more challenging then the first wave for the diagnosis of COVID-19 because of the similar ...
Timothy Hicks   +8 more
doaj   +1 more source

The impact of percutaneous epididymal sperm aspiration on sperm quality in mice

open access: yesReproduction and Fertility, 2023
In laboratory mice, sperm quality is usually assessed in spermatozoa collected from the cauda epididymidis of freshly sacrificed males. Percutaneous epididymal sperm aspiration (PESA) is a non-terminal alternative that would allow repeated sperm ...
Lisa Windhofer   +4 more
doaj   +1 more source

Dynamic Fluid Flow Exacerbates the (Pro-)Inflammatory Effects of Aerosolised Engineered Nanomaterials In Vitro

open access: yesNanomaterials, 2022
The majority of in vitro studies focusing upon particle–lung cell interactions use static models at an air–liquid interface (ALI). Advancing the physiological characteristics of such systems allows for closer resemblance of the human lung, in turn ...
Kirsty Meldrum   +3 more
doaj   +1 more source

Establishment and Characterization of the First Chinese National Standard for Nucleic Acid Amplification Technology Assays for Hepatitis E Virus Nucleic Acid Detection

open access: yesPathogens, 2023
The detection of hepatitis E virus (HEV) RNA is the gold standard for HEV infection diagnosis. In order to address the quality control requirements for HEV RNA detection kits within China, we aimed to establish the first Chinese national standard for HEV
Manyu Li   +4 more
doaj   +1 more source

Cost implications for the NHS of using the Alere™ i Influenza A & B near patient test with nasal swabs

open access: yesDiagnostic and Prognostic Research, 2018
Background Influenza is an acute viral infection of the respiratory tract. A rapid confirmatory diagnosis of influenza is important, since it is highly transmissible and outbreaks of influenza within the hospital setting increase morbidity and mortality.
A. J. Allen   +8 more
doaj   +1 more source

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