Results 1 to 10 of about 8,721,497 (397)

U1 snRNP regulates cancer cell migration and invasion in vitro

Nature Communications, 2020
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), vertebrates’
Jung-Min Oh, Chao Di, Anna Maria Pinto
exaly   +2 more sources

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

Nature Protocols, 2007
Chun-Chi Liang, Ann Y Park, Jun-Lin Guan
exaly   +2 more sources

Suspended hydrogel culture as a method to scale up intestinal organoids

Scientific Reports, 2023
Primary tissue-derived epithelial organoids are a physiologically relevant in vitro intestinal model that have been implemented for both basic research and drug development applications.
Julia Y. Co, Jessica A. Klein, Serah Kang, Kimberly A. Homan   +3 more
doaj   +1 more source

Characterization of highly expressed novel hub genes in hepatitis E virus chronicity in rabbits: a bioinformatics and experimental analysis

BMC Veterinary Research, 2022
Background Hepatitis E virus (HEV), which is the leading cause of acute viral hepatitis worldwide, usually causes self-limited infections in common individuals. However, it can lead to chronic infection in immunocompromised individuals and its mechanisms
Manyu Li, Yan Wang, Kejian Li, Haiyun Lan, Cheng Zhou   +4 more
doaj   +1 more source

Establishment and application of national reference panels for SARS-CoV-2 antigen detection kit

Biosafety and Health, 2023
To develop a national reference panel for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen detection kit and establish a quality standard. The cultures of SARS-CoV-2 and other pathogens were collected to establish a national reference
Tingting Ma, Donglai Liu, Keliang Lyu, Tingting Gao, Dawei Shi, Lanqing Zhao, Shu Shen, Yabin Tian, Sihong Xu, Haiwei Zhou   +9 more
doaj   +1 more source

Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice

Reproductive Medicine and Biology, 2022
Background The protein proAKAP4 is crucial for sperm motility and has been suggested as an indicator of male fertility. We determined the relationship between proAKAP4 concentration and sperm motility parameters in mice, and investigated the effects of ...
Auke Boersma, Jasmin Primus, Bettina Wagner, Veronika Broukal, Lill Andersen, Barbara Pachner, Maik Dahlhoff, Thomas Rülicke, Kerstin E. Auer   +8 more
doaj   +1 more source

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Cell Research, 2020
Dear Editor, In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood market in Wuhan.
Manli Wang, Ruiyuan Cao, Lei-ke Zhang, Xinglou Yang, Jia Liu, Mingyue Xu, Zhènglì Shí, Zhìhóng Hú, Wu Zhong, Gengfu Xiao   +9 more
semanticscholar   +1 more source

Comparison of immediate versus delayed frozen embryo transfer on reproductive outcome

Clinical and Experimental Obstetrics & Gynecology, 2021
The aim of this study was to compare impact of immediate versus delayed frozen frozen embryo transfer on reproductive outcome in patients undergoing IVF treatment.
Arzu Yurci, Aret Kamar, Nurettin Turktekin, Ramazan Ozyurt   +3 more
doaj   +1 more source

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Clinical Infectious Diseases, 2020
Background The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection.
Xueting Yao, F. Ye, Miao Zhang, Cheng Cui, Baoying Huang, P. Niu, X. Liu, Li Zhao, Erdan Dong, Chunli Song, S. Zhan, R. Lu, Haiyan Li, W. Tan, Dongyang Liu   +14 more
semanticscholar   +1 more source

Investigation of genotype diversity of 7,804 norovirus sequences in humans and animals of China

Open Life Sciences, 2022
Norovirus is a prominent enteric virus responsible for severe acute gastroenteritis disease burden worldwide. In our current study, we analyzed 7,804 norovirus sequences of human and animals in China which were detected from 1980 to 2020 from GenBank ...
Li Manyu, Li Kejian, Lan Haiyun, Hao Xiaotian, Liu Yan, Zhou Cheng   +5 more
doaj   +1 more source