Results 1 to 10 of about 8,565,253 (194)

U1 snRNP regulates cancer cell migration and invasion in vitro

open access: yesNature Communications, 2020
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), vertebrates’
Jung-Min Oh, Chao Di, Anna Maria Pinto
exaly   +2 more sources

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

open access: yesCell Research, 2020
Dear Editor, In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood market in Wuhan.
Manli Wang   +9 more
semanticscholar   +1 more source

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

open access: yesClinical Infectious Diseases, 2020
Background The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection.
Xueting Yao   +14 more
semanticscholar   +1 more source

Recent Progress in in vitro Models for Atherosclerosis Studies

open access: yesFrontiers in Cardiovascular Medicine, 2022
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to cardiovascular disease accounting for the high mortality in the United States.
Jun Chen   +13 more
semanticscholar   +1 more source

In vitro models and ex vivo systems used in inflammatory bowel disease

open access: yesIn vitro models, 2022
Inflammatory bowel disease (IBD) is a chronic, relapsing gastrointestinal condition. Ulcerative colitis and Crohn’s disease are types of inflammatory bowel disease.
Abhishek Joshi, A. Soni, Sanjeev Acharya
semanticscholar   +1 more source

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]

open access: yes, 2016
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R.   +13 more
core   +1 more source

A standardised static in vitro digestion method suitable for food - an international consensus.

open access: yesFood & Function, 2014
Simulated gastro-intestinal digestion is widely employed in many fields of food and nutritional sciences, as conducting human trials are often costly, resource intensive, and ethically disputable.
M. Minekus   +32 more
semanticscholar   +1 more source

INFOGEST static in vitro simulation of gastrointestinal food digestion

open access: yesNature Protocols, 2019
Developing a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract.
A. Brodkorb   +34 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy