Results 21 to 30 of about 7,982,325 (356)

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]

, 2016
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R., Benvenuto, M, Bonanno, E, Cucchi, Danilo, DE SMAELE, Enrico, DI STEFANO, Enrica, Fantini, M, Frajese, Gv, Gulino, Alberto, Masuelli, Laura, Mattera, Rosanna, Modesti, A, Orlandi, A, Screpanti, Isabella   +13 more
core   +1 more source

Does seminal fluid bacterial isolate(s) affect in vitro fertilization — embryo transfer outcome?

Middle East Fertility Society Journal, 2023
Background The chance of achieving a successful pregnancy through in vitro fertilization and embryo transfer (IVF-ET) is limited despite recent scientific advances in this field due to several factors that are known to affect the outcome.
Rukayya Muhammad Babandi, Rais Shuaibu Ibraheem, Rayyan Muhammad Garba, Idris Muhammed Liman, Amina Ismail-Are, Yakubu Samuel   +5 more
doaj   +1 more source

Transcriptomics Reveals Discordant Lipid Metabolism Effects between In Vitro Models Exposed to Elafibranor and Liver Samples of NAFLD Patients after Bariatric Surgery

Cells, 2022
Background and aims: Non-alcoholic steatohepatitis (NASH) is a life-threatening stage of non-alcoholic fatty liver disease (NAFLD) for which no drugs have been approved.
Joost Boeckmans, Alexandra Gatzios, Anja Heymans, Matthias Rombaut, Vera Rogiers, Joery De Kock, Tamara Vanhaecke, Robim M. Rodrigues   +7 more
doaj   +1 more source

Homeostatic plasticity and external input shape neural network dynamics [PDF]

Phys. Rev. X 8, 031018 (2018), 2018
In vitro and in vivo spiking activity clearly differ. Whereas networks in vitro develop strong bursts separated by periods of very little spiking activity, in vivo cortical networks show continuous activity. This is puzzling considering that both networks presumably share similar single-neuron dynamics and plasticity rules. We propose that the defining
arxiv   +1 more source

In Vitro Fermentability, Degradability and Microbial Biomass Product of Complete Ration Containing a Combination of Field Grass, Concentrate and Nutrient Rich Supplement [PDF]

, 2009
The objective of this experiment was to obtain an optimum combination between field grass,concentrate and Nutrient Rich Supplement (NRS) based on in vitro study using Hohenheim gas test. Theexperimental diets were: R1 (control diet = 70% field grass + 30%
Suharyono, S. (S), Tjakradidjaja, A. S. (A), Wahyuni, D. S. (D)   +2 more
core   +1 more source

Lipid droplets in granulosa cells are correlated with reduced pregnancy rates

Journal of Ovarian Research, 2020
Background Lipids are an important source for energy production during oocyte maturation. The accumulation of intracellular lipids binds to proteins to form lipid droplets. This may lead to cellular lipotoxicity. The impact of lipotoxicity on cumulus and
Shira Raviv, Shay Hantisteanu, Shilhav Meisel Sharon, Yuval Atzmon, Mediea Michaeli, Einat Shalom-Paz   +5 more
doaj   +1 more source

Step-Down of FSH- Dosage During Ovarian Stimulation – Basic Lessons to Be Learnt From a Randomized Controlled Trial

Frontiers in Endocrinology, 2021
A rise in serum progesterone in the late follicular phase is a well described adverse effect of ovarian stimulation for IVF/ICSI. Previous data suggest, that enhanced gonadotropin stimulation causes progesterone elevation and the incidence of premature ...
Barbara Lawrenz, Barbara Lawrenz, Carol Coughlan, Laura Melado, Shieryl Digma, Junard Sibal, Alliza Jean, Human M. Fatemi   +7 more
doaj   +1 more source

In-vitro gastrointestinal digestion of kenaf seed oil-in-water nanoemulsions [PDF]

, 2016
The high nutrition value of kenaf seed oil has good potential to be used as functional foods or nutraceutical products. Kenaf seed oil-in-water nanoemulsions stabilised by ternary emulsifier mixtures, namely sodium caseinate, gum Arabic and Tween 20 were
Cheong, Ai Mun, Nyam, Kar Lin, Tan, Chin Ping   +2 more
core   +1 more source

Electrospun nanofibers in cancer research: from engineering of in vitro 3D cancer models to therapy [PDF]

Biomaterials Science, 2020, 2021
Electrospinning is historically related to tissue engineering due to its ability to produce nano-/microscale fibrous materials with mechanical and functional properties that are extremely similar to those of the extracellular matrix of living tissues. The general interest in electrospun fibrous matrices has recently expanded to cancer research both as ...
arxiv   +1 more source

Cinética da maturação nuclear in vitro de oócitos bubalinos

Brazilian Journal of Veterinary Research and Animal Science, 2002
Com o objetivo de avaliar a cinética da maturação in vitro de oócitos bubalinos, foram cultivados 1.619 oócitos com cumulus oophorus compacto em quatro diferentes tratamentos: T1 - TCM 199 com 10% de Soro Fetal Bovino (SFB) (meio base); T2 - Meio base e ...
Simone do Socorro Damasceno Santos, Jedina Kato Dantas, Moysés dos Santos Miranda, Flávia Costa Biondi, Otávio Mitio Ohashi   +4 more
doaj   +1 more source