Results 31 to 40 of about 8,721,497 (397)

Distinct and Dynamic Transcriptome Adaptations of iPSC-Generated Astrocytes after Cytokine Stimulation

open access: yesCells, 2022
Astrocytes (ACs) do not only play a role in normal neurogenesis and brain homeostasis, but also in inflammatory and neurodevelopmental disorders. We studied here the different patterns of inflammatory activation triggered by cytokines in human induced ...
Anna-Sophie Spreng   +4 more
doaj   +1 more source

A robust bacterial high-throughput screening system to evaluate single nucleotide polymorphisms of human homogentisate 1,2-dioxygenase in the context of alkaptonuria

open access: yesScientific Reports, 2022
Alkaptonuria (AKU) is a rare inborn error of metabolism caused by a defective homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the tyrosine degradation pathway.
Sien Lequeue   +5 more
doaj   +1 more source

An Attempt to Polarize Human Neutrophils Toward N1 and N2 Phenotypes in vitro

open access: yesFrontiers in Immunology, 2020
Neutrophils act as the first line of defense against invading pathogens. Although traditionally considered in context of their antimicrobial effector functions, the importance of tumor-associated neutrophils (TANs) in the development of cancer has become
Mareike Ohms, Sonja Möller, T. Laskay
semanticscholar   +1 more source

Bioavailability and bioaccessibility of food bioactive compounds; overview and assessment by in vitro methods.

open access: yesComprehensive Reviews in Food Science and Food Safety, 2020
Oral bioavailability is the key to the bioefficiency of food bioactive ingredients; it evaluates the relationship between foods and their health benefits.
C. Dima   +3 more
semanticscholar   +1 more source

In Vitro Characterization of Scaffolds for Tissue Engineering - A Review [PDF]

open access: yes, 2016
Scaffolds are artificial structures that replace the natural extracellular matrix (ECM). Scaffolds are capable of supporting three dimensional tissue formations.
Baliga, A. (Aarti)   +1 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

An In Vitro Microneutralization Assay for SARS‐CoV‐2 Serology and Drug Screening

open access: yesCurrent Protocols in Microbiology, 2020
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged in the city of Wuhan, Hubei Province, China, in late 2019. Since then, the virus has spread globally and caused a pandemic.
F. Amanat   +12 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

In Vitro Fermentation Characteristics and Rumen Microbial Population of Diet Supplemented with Saccharomyces Cerevisiae and Rumen Microbe Probiotics [PDF]

open access: yes, 2016
The objective of this study was to select three strains of probiotic Saccharomyces cerevisiae and to evaluate the effect of S. cerevisiae and rumen bacteria isolate (MR4) supplementation and their combination on rumen fermentability and rumen microbial ...
Evvyernie, D. (Dwierra)   +2 more
core  

Scaffolds for 3D in vitro culture of neural lineage cells. [PDF]

open access: yes, 2017
Understanding how neurodegenerative disorders develop is not only a key challenge for researchers but also for the wider society, given the rapidly aging populations in developed countries.
Cameron, Neil R.   +3 more
core   +1 more source

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