Results 61 to 70 of about 7,982,325 (356)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Stochastic Molecular Reaction Queueing Network Modeling for In Vitro Transcription Process [PDF]

arXiv, 2023
To facilitate a rapid response to pandemic threats, this paper focuses on developing a mechanistic simulation model for in vitro transcription (IVT) process, a crucial step in mRNA vaccine manufacturing. To enhance production and support industry 4.0, this model is proposed to improve the prediction and analysis of IVT enzymatic reaction network.
arxiv  

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

FEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet, Magali Leroy, Alexandre Maes, Ciarán Condon, Frédérique Braun   +4 more
wiley   +1 more source

Burden of non-COVID-19 lower respiratory infections in China (1990–2021): a global burden of disease study analysis

Respiratory Research
Background The assessment of lower respiratory infection (LRI) mortality, incidence, and responsible pathogens in China provides a scientific basis for the prevention and management of LRI, especially for evaluating the impact of coronavirus disease 2019
Manyu Li, Zeyu Song, Wenjun Wan, Haiwei Zhou   +3 more
doaj   +1 more source

Perbanyakan In Vitro Dendrobium Indonesia Raya ‘Ina' melalui Embriogenesis Somatik Berbasis Sistem Bioreaktor [PDF]

, 2016
An effective and efficient in vitro propagation system has important roles in preparing and producing high quality-seedlings of Dendrobium for commercial scale. The objective of this research was to establish an effective and efficient embryogenic callus
Mattjik, N. A. (Nurhajati), Purwito, A. (Agus), Rachmawati, F. (Fitri), Wiendi, N. M. (Ni), Winarto, D. B. (dan)   +4 more
core  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Studi In Vitro Potensi Kurkuminoid (Curcuma Domestica Vahl) dan Senyawa-senyawanya terhadap Superoksidadismutase dan pada Proses Peroksidasi Lipid Sel Monosit. [PDF]

, 2000
Tujuan penelitian adalah untuk mengetahui apakah masing-masing sampel ( kurkuminoid,kurkumin, desmetoksikurkumin dan bisdesmetoksikurkumin ) dengan dosis sama (3,68 ug/50ul)yang diisolasi dan dimurnikan dari rimpang kunyit (Curcuma domestica Vahl ...
Adianto, N. I. (Nenden), Kamara, D. S. (Dian), Koeswadji, K. (Koeswadji), Sidik, S. (Sidik)   +3 more
core  

In vitro efficacy of emamectin benzoate and glyphosate against monogenean parasites from Colossoma macropomum. [PDF]

Este estudo investigou a eficácia in vitro do benzoato de emamectina e do glifosato contra monogenéticos de Colossoma macropomum e a tolerância dessa espécie a essas drogas terapêuticas.
ALVES, C. M. G., BAIA, R. R. J., MALHEIROS, D. F., SANTOS, G. G., TAVARES-DIAS, M.   +4 more
core   +1 more source

In vitro germination of wheat pollen on raffinose medium [PDF]

, 1992
Wheat pollen gave up to 81.7 % germination when cultured on a 0.7 % agar medium containing 100 mg 1−1 H3BO3, 300 mg 1−1 CaCl2.2H2O and 0.75 M raffinose.
Cheng, C., McComb, J.A.
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source