published quarterly. The aim of IJPBS is to publish. peer reviewed research and review articles rapidly without delay in the developing field of pharmaceutical and biological ...
Cladophora Rupestris +2 more
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Pemanfaatan Teknik Kultur in Vitro Untuk Konservasi Plasma Nutfah Ubi-ubian [PDF]
, 2014 Except for potato, sweet potato, taro, yam, andcassava, most of tuber crops are considered as underutilizedcrops. However, tuber crops are potential as alternativecarbohydrate sources, so they can be used as food reservesto face global climate change ...
Dewi, I. S. (Iswari) +2 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro [PDF]
, 2023 Chang Wang +7 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Establishing endotoxin limits to enhance the reliability of in vitro immunogenicity risk assessments
mAbsImmunogenic responses to biotherapeutics often lead to termination of their development because the resulting anti-drug-antibodies (ADA) can negatively impact pharmacology, safety, and efficacy.
Yun Hee Jeong +4 more
doaj +1 more source
Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma
Frontiers in Oncology, 2019 Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in foods such as coffee, wine, tea, and popular medicines such as propolis.
Kaio Murilo Monteiro Espíndola +7 more
doaj +1 more source
Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH
MethodsX, 2020 Non-alcoholic steatohepatitis (NASH) is a severe chronic liver disease that affects 3 to 5 percent of the world population. It is characterized by hepatic lipid accumulation and inflammation and can progress towards fibrosis, cirrhosis and hepatocellular
Joost Boeckmans +7 more
doaj +1 more source
Pelestarian secara In Vitro melalui Metode Pertumbuhan Lambat pada Beberapa Genotipe Ubi Jalar (Ipomea Batatas (L) Lam) [PDF]
, 2013 The objectives of this research were to estimate responses of several sweet potato genotypes in preservation media through in vitro slow growth preservation, and to achieve cheap and accessible media.
Laisina, J. K. (Jean)
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source