Results 81 to 90 of about 7,982,325 (356)

In Vitro Culture Manipulation on Pruatjan for Secondary Metabolite Production [PDF]

, 2007
Purwoceng (Pimpinella pruatjan Molk. atau Pimpinellaalpina KDS.) adalah tanaman obat langka yang dapat dimanfaatkansebagai bahan obat afrodisik, diuretik, dan tonik.Kultur in vitro tidak hanya dapat digunakan untuk konservasidan perbanyakan tanaman ...
Darwati, I. (Ireng), Mariska, I. (Ika), Purnamaningsih, R. (Ragapadmi), Roostika, I. (Ika)   +3 more
core  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism

Cell Death and Disease
Neurite degeneration (ND) precedes cell death in many neurodegenerative diseases. However, it remains unclear how this compartmentalized cell death process is orchestrated in the central nervous system (CNS).
Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist   +5 more
doaj   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

The Fibrotic Phenotype of Human Precision-Cut Lung Slices Is Maintained after Cryopreservation

Toxics
Human precision-cut lung slices (hPCLS) prepared from fibrotic lungs recapitulate the pathophysiological hallmarks of fibrosis. These hallmark features can also be induced by treating non-fibrotic hPCLS with a fibrotic cocktail (FC).
Méry Marimoutou, Vivek Patel, Jae Hun Kim, Niccole Schaible, Jose Alvarez, Joseph Hughes, McKenzie Obermok, Carlos Iván Rodríguez, Thomas Kallarakal, Béla Suki, Khalid Amin, Ramaswamy Krishnan, Holger Peter Behrsing   +12 more
doaj   +1 more source

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

Frontiers in Oncology, 2019
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in foods such as coffee, wine, tea, and popular medicines such as propolis.
Kaio Murilo Monteiro Espíndola, Roseane Guimarães Ferreira, Luis Eduardo Mosquera Narvaez, Amanda Caroline Rocha Silva Rosario, Agnes Hanna Machado da Silva, Ana Gabrielle Bispo Silva, Ana Paula Oliveira Vieira, Marta Chagas Monteiro   +7 more
doaj   +1 more source

Konservasi in Vitro Tanaman Jeruk Besar (Citrus Maxima (Burm.) Merr.) Kultivar Srinyonya Menggunakan Osmotikum Dan Retardan [PDF]

, 2010
In Vitro Conservation of Pomelo (Citrus maxima (Burm.)Merr.) cv Srinyonya Using Osmoticum and Retardant.Iswari S. Dewi, Gani Jawak, Ika Roostika, M. Sabda,Bambang S. Purwoko, and Widiati H. Adil.
Adil, W. H. (Widiati), Dewi, I. S. (Iswari), Jawak, G. (Gani), Purwoko, B. S. (Bambang), Roostika, I. (Ika), Sabda, M. (Muhammad)   +5 more
core  

In vitro and in vivo characterisation of Listeria monocytogenes outbreak isolates [PDF]

, 2019
Listeriosis is an important food-borne disease responsible for high rates of morbidity and mortality. L. monocytogenes has been the cause of several foodborne outbreaks and its ability to adapt and survive in a wide range of environmental conditions ...
Corcionivoschi, Nicolae, Couto, Jillian M., Criste, Adriana, Dorrell, Nick, Gundogdu, Ozan, Ijaz, Umer Zeeshan, Kelly, Carmel, Linton, Mark, McBride, Jane, Pet, Ioan, Pinkerton, Laurette, Scates, Pam, Sloan, William T., Stef, Ducu, Stef, Lavinia, Stratakos, Alexandros Ch., Ward, Patrick, Wren, Brendan W.   +17 more
core   +3 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

In vitro and sensory tests to design easy-to-swallow multi-particulate formulations [PDF]

arXiv, 2018
Flexible dosing and ease of swallowing are key factors when designing oral drug delivery systems for paediatric and geriatric populations. Multi-particulate oral dosage forms can offer significant benefits over conventional capsules and tablets. This study proposes the use of an in vitro model to quantitatively investigate the swallowing dynamics in ...
arxiv