Results 81 to 90 of about 8,658,473 (396)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism

open access: yesCell Death and Disease
Neurite degeneration (ND) precedes cell death in many neurodegenerative diseases. However, it remains unclear how this compartmentalized cell death process is orchestrated in the central nervous system (CNS).
Markus Brüll   +5 more
doaj   +1 more source

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

open access: yesFrontiers in Oncology, 2019
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in foods such as coffee, wine, tea, and popular medicines such as propolis.
Kaio Murilo Monteiro Espíndola   +7 more
doaj   +1 more source

Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH

open access: yesMethodsX, 2020
Non-alcoholic steatohepatitis (NASH) is a severe chronic liver disease that affects 3 to 5 percent of the world population. It is characterized by hepatic lipid accumulation and inflammation and can progress towards fibrosis, cirrhosis and hepatocellular
Joost Boeckmans   +7 more
doaj   +1 more source

Kultur in Vitro Endosperma, Protokol Yang Efisien Untuk Mendapatkan Tanaman Triploid Secara Langsung [PDF]

open access: yes, 2010
In Vitro Culture of Endosperm: An efficient protocol topropagate triploid plants directly. L. Agus Sukamto.Triploid plants are very vigorous and beneficial since theygenerally produce seedless fruits, bigger flowers, and producemore volume of wood than ...
Sukamto, L. A. (Lazarus)
core  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Research Article [PDF]

open access: yes
published quarterly. The aim of IJPBS is to publish. peer reviewed research and review articles rapidly without delay in the developing field of pharmaceutical and biological ...
Cladophora Rupestris   +2 more
core  

Mucolytic In Vitro Activity Of Ethanolic Extract Of Hibiscus Rosa-sinensis L. Red Straight Crown [PDF]

open access: yes, 2015
Ethanolic extract of red shoe flower (Hibiscus rosa-sinensis L.) has been known to decrease mucus viscosity by in vitro. The aim of this study is to evaluate the effect of various concentration of the extract in syrup for decreasing mucus viscosity and ...
Murrukmihadi, M. (Mimiek)   +1 more
core  

Toward in vitro fertilization in Brachiaria spp. [PDF]

open access: yes, 2010
Brachiaria are forage grasses widely cultivated in tropical areas. In vitro pollination was applied to accessions of Brachiaria spp. by placing pollen of non-dehiscent anthers on a solid medium near isolated ovaries.
Alves, E.R.   +5 more
core   +2 more sources

The legal status of in vitro embryos

open access: yes, 2014
Our science has advanced greatly and continues to do so. While being witnesses to this phenomenon, we are not yet ready to fully accept all of its results which can lead to the improvements of our biological structure, or our lives, in other words. There
Sandra Samardzic
semanticscholar   +1 more source

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