Results 11 to 20 of about 88,172 (307)

In vitro dissolution of dapsone

Journal of Pharmacy and Pharmacology, 1981
Abstract Log normal samples of dapsone (DDS) were prepared in which the geometric mean diameter ranged from 20 to 50 μm while the geometric standard deviation was in the range 1·62 to 1·88. Using a simple in vitro flow-through dissolution cell at 37°C, the data obtained were found to fit the Hixson-Crowell cube root dissolution law up to
J, Swarbrick, D, Ma
openaire   +3 more sources

Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets

Malaria Journal, 2020
Background Dissolution of artemether (ART) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets is one of the critical quality attributes. Thus, the verification of the release profile of ART and
Sileshi Belew, Sultan Suleman, Markos Duguma, Henok Teshome, Evelien Wynendaele, Luc Duchateau, Bart De Spiegeleer   +6 more
doaj   +1 more source

First-Principles and Empirical Approaches to Predicting In Vitro Dissolution for Pharmaceutical Formulation and Process Development and for Product Release Testing [PDF]

AAPS Journal, 2019
Zhenqi Shi, André Hermans, Md Anik Alam   +2 more
exaly   +2 more sources

Cocrystallization of gliclazide with improved physicochemical properties

Future Journal of Pharmaceutical Sciences, 2021
Background Cocrystallization is one of the crystal engineering strategies used to alter the physicochemical properties of drugs that are poorly water-soluble.
Shivarani Eesam, Jaswanth S. Bhandaru, Raghuram Rao Akkinepally, Ravi Kumar Bobbala   +3 more
doaj   +1 more source

Instant Formulation of Inhalable Beclomethasone Dipropionate—Gamma-Cyclodextrin Composite Particles Produced Using Supercritical Assisted Atomization

Pharmaceutics, 2023
Medical composites derived from Gamma-cyclodextrin (γ-CD) and beclomethasone dipropionate−gamma-cyclodextrin (BDP−γ-CD) are synthesized over supercritical-assisted atomization (SAA) herein.
Hsien-Tsung Wu, Han-Cyuan Lin, Yi-Jia Tu, Kim Hoong Ng   +3 more
doaj   +1 more source

The role of sodium lauryl sulfate on formulation of directly compressed tablets containing simvastatin and aspirin: Effect on drugs dissolution and gastric mucosa

Saudi Pharmaceutical Journal, 2022
According to the American College of Cardiology/American Heart Association (ACC/AHA), both aspirin and statin are used in the primary prevention of cardiovascular diseases. Aspirin (ASA) is contraindicated if there is gastrointestinal bleeding because it
Doaa H. Alshora, Mohamed A. Ibrahim, Gamal Zayed, Mohammed A. Al Rwashed, Heba A. Abou-Taleb, Marwa F. Ali   +5 more
doaj   +1 more source

Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification [PDF]

, 2017
Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance is highly or poorly soluble.
Raimar Löbenberg, Beatriz Ayumi Sakamoto Kakuda, Duque, Marcelo Dutra [UNIFESP], Ferraz, Humberto Gomes, Silva, Daniela Amaral, Sakamoto Kakuda, Beatriz Ayumi [UNIFESP], Carpentieri Rodrigues, Leticia Norma [UNIFESP], Daniela Amaral Silva, Humberto Gomes Ferraz, Lobenberg, Raimar, Marcelo Dutra Duque, Michele Georges Issa, Issa, Michele Georges, Leticia Norma Carpentieri Rodrigues   +13 more
core   +1 more source

Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine) [PDF]

, 2007
Different liquisolid formulations of carbamazepine were accomplished by dissolving the drug in the non-toxic hydrophilic liquids, and adsorbing the solution onto the surface of silica.
Yousef Javadzadeh, Jafari-Navimipour, Baharak, Javadzadeh, Yousef, Yousef Javadzadeh (16203113), Baharak Jafari-Navimipour (16203116), Ali Nokhodchi, Baharak Jafari-Navimipour, Nokhodchi, Ali, Ali Nokhodchi (4465915)   +8 more
core   +1 more source

Investigation of variability of primary materials on the intrinsic dissolution behavior of carbamazepine [PDF]

, 2008
Carbamazepine (CBZ) is a poorly water soluble drug, classified as class II according to the Biopharmaceutics Classification System and exhibits at least four polymorphic forms and a dihydrate.
Sehic, Selma
core   +1 more source

Biopharmaceutical relevance of dissolution profile comparison: Proposal of a combined approach [PDF]

, 2014
The aims of the present study were to evaluate the performance of the main methods proposed for the comparison of percentage dissolved versus time curves and to recommend a more biorelevant combined approach for the comparison of dissolution profiles of ...
Ruiz, María Esperanza, Volonté, María Guillermina   +1 more
core   +2 more sources