Results 91 to 100 of about 549,804 (200)

Editorial: New mechanisms and drugs for the treatment of cardiovascular disease with diabetes

Frontiers in Cardiovascular Medicine, 2023
Shanshan Zhang, Shanshan Zhang, Shanshan Zhang, Jingwei Li, Yuli Huang, Jie Yu, Xiong-Fei Pan, Xiong-Fei Pan   +7 more
doaj   +1 more source

Antioxidents or reduced oxygen tension as a defense system in T cells ex vivo and in vitro

, 2009
Age-related deterioration and dysregulation of T cell function, termed ‘immunosenescence’, may lead to increased mortality and morbidity in humans through greater susceptibility to infections and disease.
Marthandan, SS, Marthandan, Shiva Shankar   +1 more
core  

Telescopic crowns: extra-oral and intra-oral retention force measurement--in vitro/in vivo correlation

, 2011
This study deals with the determination of the retentive forces of telescopic crowns measured extra- and intra-orally and the correlation of these ...
Stark, Helmut, Ludger Keilig, Norbert Enkling, Dominik Kraus, Enkling, Norbert, Lina Gölz, Kraus, Dominik, Gölz, Lina, Anja Hansen, Stefan Bayer, Bayer, Stefan, Hansen, Anja, Helmut Stark, Keilig, Ludger   +13 more
core   +1 more source

In vitro-in vivo correlation of drug release profiles from medicated contact lenses using an in vitro eye blink model. [PDF]

Drug Deliv Transl Res, 2023
Pereira-da-Mota AF, Vivero-Lopez M, Garg P, Phan CM, Concheiro A, Jones L, Alvarez-Lorenzo C.   +6 more
europepmc   +1 more source

In vitro-to-in vivo correlation of the skin penetration, liver clearance and hepatotoxicity of caffeine

, 2015
This work illustrates the use of Physiologically-Based Toxicokinetic (PBTK) modelling in in vitro-to-in vivo correlation (IVIVC) of kinetic measures of caffeine skin penetration and liver metabolism, as well as dose metrics of caffeine-induced HepaRG ...
SALA BENITO Jose', PAINI Alicia, BURTON Julien, URANI Chiara, GAJEWSKA Monika, BRIESEN Heiko, WORTH Andrew, SCHRAMM Karl-Werner   +7 more
core   +1 more source

In Vitro-In Vivo Correlation of Posaconazole-Amphotericin B Combination against Candida albicans: In Vitro Interacting Concentrations Are Associated with In Vivo Free Drug Levels. [PDF]

J Fungi (Basel), 2023
Meletiadis J, Beredaki MI, Elefanti A, Pournaras S, Muller A.   +4 more
europepmc   +1 more source

Establishment of Level a In Vitro-In Vivo Correlation (IVIVC) via Extended DoE-IVIVC Model: A Donepezil Case Study. [PDF]

Pharmaceutics, 2022
Lee DY, Shin S, Kim TH, Shin BS.
europepmc   +1 more source

In vitro models for the blood-brain barrier

, 2005
The aim of the present study was to identify a model for the blood-brain barrier based on the use of a continuous cell line, and to investigate the specificity of this model.
Osterberg, T., Stanimirovic, D., Nilsson, J., Terasaki, T., Fenart, Laurence, Öberg, J.-O., Garberg, P., Mabondzo, Aloïse, M., Raub, T. J., Ball, M., Hurst, D. R., Oberg, J., Hurst, R., Raub, T., Cecchelli, Roméo, Fenart, L., Ball, Marguerite, Mabondzo, A., Stanimirovic, Danica, Nilsson, J. E., Borg, N., Cecchelli, R., Lindmark, T.   +22 more
core  

Correlation of Cidality under physiology of in-vitro vs. in-vivo.

, 2016
The low pH condition appears to be the ideal screening system (R = 0.9856) showing linearity during a correlation of different in-vitro screens of alternate stress responses versus the in-vivo outcome for selection of cidal inhibitors.
Nanduri Robert (2657527), Parvinder Kaur (235201), Anand Anbarasu (539441), Sudha Ramaiah (539442), Upneet K. Sokhi (470793), Radha Krishan Shandil (2657530), Supreeth Guptha (1734121), Shridhar Narayanan (456463), Santanu Datta (141626), Naveen Kumar (66313)   +9 more
core   +1 more source

Formulation of Enalapril Maleate Nanoproniosomal Gels and Their Pharmacokinetic Evaluations in Hypertensive Albino Wistar Rats: Ex Vivo and In Vivo Approaches

Nano Biomedicine and Engineering
Proniosomes are drug-encapsulated, nanoscale vesicular structures that generate multilamellar niosomal dispersions upon hydration. This study aimed to develop enalapril maleate nanoproniosomal gels and assess their effectiveness in experimental ...
Mekala Sabareesh, Jayaraman Rajangam, Janapati Pedda Yanadaiah   +2 more
doaj   +1 more source