Results 71 to 80 of about 549,804 (200)

Development of novel risperidone implants using blends of polycaprolactones and in vitro in vivo correlation studies

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2014
The objective of this study was to develop a novel implant containing risperidone intended for long-term treatment in Schizophrenia utilizing in vitro in vivo correlation (IVIVC) studies.
Aerrolla Navitha   +3 more
doaj   +1 more source

Development of a Physiologic In-Vitro Testing Methodology for Assessment of Cervical Spine Kinematics [PDF]

open access: yes, 2013
In-vitro biomechanical testing has been critical in the design and evaluation of spinal surgical instrumentation, however determination of realistic physiologic loading levels has proven difficult outside of the in-vivo setting.
Bell, Kevin
core  

Estudio de la correlación in vitro – in vivo de la liberación de 6-metilcumarina a partir de un sistema micropartículado [PDF]

open access: yes, 2016
La correlación in vitro – in vivo, es el establecimiento de un modelo matemático predictivo que describe la relación entre una característica del perfil de liberación in vitro y una respuesta in vivo, generalmente en términos del comportamiento ...
Cárdenas Cuadros, Paola Andrea
core  

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results

open access: yes, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Madan Rehani   +2 more
core  

In Vitro and In Vivo Assessment of Pharmacokinetic Profile of Peramivir in the Context of Inhalation Therapy

open access: yesPharmaceuticals
Objective: The aim was to evaluate the pharmacokinetics and underlying mechanisms of peramivir, a clinically approved antiviral agent for severe influenza, subsequent to airway inhalation in rats, thereby surmounting the constraints associated with the ...
Liuhan Dong   +5 more
doaj   +1 more source

Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length [PDF]

open access: yes, 1992
Alkylcyanoacrylate particles were physico-chemically characterized in terms of size, surface charge, zeta potential, interaction with charged serum components and surface hydrophobicity as relevant parameters influencing the in vitro interaction with ...
Müller, R. H.   +4 more
core   +1 more source

Correlation of the appearance of the keratoconic cornea in vivo by confocal microscopy and in vitro by light microscopy

open access: yes, 2005
OBJECTIVE: To compare morphologic features of keratoconus as observed in vivo with a slit scanning confocal microscope and in vitro using light microscopy.
Bonshek, Richard E.   +2 more
core  

Endostar-loaded PEG-PLGA nanoparticles: in vitro and in vivo evaluation

open access: yes, 2010
Sanyuan Hu1, Yangde Zhang21Xiangya School of Medicine and 2National Hepatobiliary and Enteric Surgery Research Center, Ministry of Health, Central South University, Changsha, Hunan Province, People’s Republic of ChinaAbstract: Endostar, a novel
null Hu   +3 more
core   +1 more source

Study on the non labeled synthetic colorants were detected in natural food pigments and condiment

open access: yesZhongguo shipin weisheng zazhi
ObjectiveThe method of high performance liquid chromatography (HPLC) was developed to study the detection of synthetic colorants in natural pigments and condiment.MethodsThe analytes were extracted by direct ultrasonic extraction with water. The analytes
WEI Yutao   +8 more
doaj   +1 more source

Comparisons of in vitro Fick’s first law, lipolysis, and in vivo rat models for oral absorption on BCS II drugs in SNEDDS

open access: yesInternational Journal of Nanomedicine, 2019
Jingyi Ye,1,* Huiyi Wu,1,* Chuanli Huang,1 Wanting Lin,2 Caifeng Zhang,1 Bei Huang,2 Banyi Lu,2 Hongyu Xu,2 Xiaoling Li,3 Xiaoying Long1,41Department of Pharmaceutics, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, People&
Ye J   +9 more
doaj  

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