Results 111 to 120 of about 701,007 (399)

HUNK Phosphorylates Rubicon to Support Autophagy [PDF]

, 2019
Background: Autophagy is a catabolic cellular recycling pathway that is essential for maintaining intracellular homeostasis. Autophagosome formation is achieved via the coordination of the Beclin-1 protein complex.
Abt, Melissa, Eblen, Scott T., Muise-Helmericks, Robin, Rhett, J. Matthew, Yeh, Elizabeth S., Zambrano, Joelle N.   +5 more
core   +1 more source

Flow-enhanced vascularization and maturation of kidney organoids in vitro

Nature Methods, 2018
Kidney organoids derived from human pluripotent stem cells have glomerular- and tubular-like compartments that are largely avascular and immature in static culture.
Kimberly A. Homan, Navin R Gupta, Katharina T. Kroll, David B. Kolesky, Mark A. Skylar-Scott, Tomoya Miyoshi, Donald Mau, M. T. Valerius, Thomas C. Ferrante, Joseph V. Bonventre, Jennifer A. Lewis, Ryuji Morizane   +11 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Effect of Kaempferol on In Vitro Maturation of Porcine Oocytes

Scientific Papers Animal Science and Biotechnologies, 2023
We investigated the effects of kaempferol on porcine oocytes in vitro maturation. Kaempferol is one the most studied flavonoids and is in research attention on animal cells until 1979.
Delia Orlovschi, Ileana Miclea, Marius Zahan, Vasile Miclea   +3 more
doaj  

Angiopoietins differentially influence in vitro angiogenesis by endothelial cells of different origin [PDF]

, 2011
Angiopoietins are important growth factors for vascular development and quiescence. They are promising targets for pro-or anti-angiogenic therapies in diverse pathologies, but the mechanisms of the ANGPT/TIE2 system are complex and not well understood ...
Bahramsoltani, Mahtab, Cornillie, Pieter, De Spiegelaere, Ward, Plendl, Johanna, Van Den Broeck, Wim   +4 more
core   +2 more sources

The complex TIE between macrophages and angiogenesis [PDF]

, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M., Avraham‐Davidi I., Baer C., Bailey A. S., Barnett F. H., Bonnardel J., Chakarov S., Chen L., Coffelt S. B., Corliss B. A., Cursiefen C., Daly C., Davies L. C., Davies L. C., De Palma M., De Palma M., De Palma M., De Palma M., De Palma M., De Spiegelaere W., DeFalco T., Deshmane S. L., Detry B., Dimova I., Dimova I., Eklund L., Elamaa H., Eubank T. D., Fantin A., Ferrari G., Fukuhara S., Ganta V. C., Ganta V. C., García S., Gerri C., Grunewald M., Guo L., Gurevich D. B., Hamm A., Hazan A. D., He H., Hoeffel G., Itoh M., Jetten N., Kim M., Kochhan E., Korhonen E. A., Korpelainen E. I., Krishnasamy K., Kumar A. H., Leibovich S. J., Lim H. Y., Liu C., Lucas T., Master Z., Metharom P., Michaeli S., Moldovan N. I., Moore E. M., Mueller S. B., Murdoch C., Murray P. J., Patel A. S., Polverini P. J., Potente M., Pucci F., Saharinen P., Saharinen P., Schif‐Zuck S., Schmeisser A., Seaman S. A., Seok S. H., Spiller K. L., Venneri M. A., Vestweber D., Webster N. L., West M. E. D., Willenborg S., Yamamoto S., Zajac E., Zenker D., Zhang W.   +81 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

FERTILIZACION DE OVOCITOS CAPRINOS MADURADOS EN DOS MEDIOS DE CULTIVO

Tropical and Subtropical Agroecosystems, 2010
El objetivo del estudio fue evaluar el efecto de dos medios de cultivo en la tasa de maduración y fertilización de ovocitos de cabra. Los complejos cumulus ovocito (CCO´s) fueron obtenidos de ovarios de cabras post-mortem. En el experimento I (EXP I),
Alejandra Soberano Martinez, A. Bravo, I. Olivo, I. Toscano, M. Cajero, J. Herrera, M. Navarro, J. Segura   +7 more
doaj  

Biological and physiological characteristics of human cumulus cells in adherent culture condition

International Journal of Reproductive BioMedicine, 2020
Background: Cumulus cells, as oocyte nurse cells, provide a suitable microenvironment with growth factors and cellular interactions required for oocyte maturation.
Somayyeh Sadat Tahajjodi, Ehsan Farashahi Yazd, Azam Agha-Rahimi, Reza Aflatoonian, Mohammad Ali Khalili, Mahnaz Mohammadi, Behrouz Aflatoonian   +6 more
doaj   +1 more source

Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid [PDF]

, 2012
During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins.
Angela M. Gronenborn, Christopher Aiken, Danxia Ke, Ernest Yufenyuy, Gongpu Zhao, Jinwoo Ahn, Jiying Ning, John A. T. Young, Maria DeLucia, Peijun Zhang, Xin Meng   +10 more
core   +4 more sources