Results 91 to 100 of about 114,426,039 (308)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Vaccinia Virus Infection Requires Maturation of Macropinosomes. [PDF]

, 2015
The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake.
Mercer, Jason, Rizopoulos, Zaira, Balistreri, G, Kilcher, S, Mercer, J, Syedbasha, M, Kilcher, Samuel, Helenius, Ari, Balistreri, Giuseppe, Rizopoulos, Z, Syedbasha, Mohammedyaseen, Martin, Caroline K., Martin, CK, Helenius, A   +13 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Effect of Kaempferol on In Vitro Maturation of Porcine Oocytes

Scientific Papers Animal Science and Biotechnologies, 2023
We investigated the effects of kaempferol on porcine oocytes in vitro maturation. Kaempferol is one the most studied flavonoids and is in research attention on animal cells until 1979.
Delia Orlovschi, Ileana Miclea, Marius Zahan, Vasile Miclea   +3 more
doaj  

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Candrian, Christian, Gianni-Barrera, Roberto, Juelke, Henriette, Martin, Ivan, Jaquiery, Claude, Acharya, Chitrangada, Barbero, Andrea, Miot, Sylvie, Pelttari, Karoliina, Mainil-Varlet, Pierre   +9 more
core   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Biological and physiological characteristics of human cumulus cells in adherent culture condition

International Journal of Reproductive BioMedicine, 2020
Background: Cumulus cells, as oocyte nurse cells, provide a suitable microenvironment with growth factors and cellular interactions required for oocyte maturation.
Somayyeh Sadat Tahajjodi, Ehsan Farashahi Yazd, Azam Agha-Rahimi, Reza Aflatoonian, Mohammad Ali Khalili, Mahnaz Mohammadi, Behrouz Aflatoonian   +6 more
doaj   +1 more source

Supplementation of fetal bovine serum alters histone modification H3R26me2 during preimplantation development of in vitro produced bovine embryos [PDF]

, 2015
In vitro production (IVP) of bovine embryos is not only of great economic importance to the cattle industry, but is also an important model for studying embryo development.
Corrêa, Carolina A.P. [UNESP], Laura L.G. Lorena, João C.T. Penteado, Mingoti, Gisele, Penteado, João C.T., Lorena, Laura L.G., Arnold, Daniel R., Rossi, Guilherme F. [UNESP], Daniel R. Arnold, Guilherme F. Rossi, Flavia L. Lopes, Lopes, Flavia L. [UNESP], Rossi, Guilherme F., Ifran, Aderson M. [UNESP], Carolina A.P. Corrêa, Gaspar, Roberta C., Mingoti, Gisele [UNESP], Gisele Mingoti, Roberta C. Gaspar, Lorena, Laura L.G. [UNESP], Aderson M. Ifran, Corrêa, Carolina A.P., Ifran, Aderson M., Lopes, Flavia L., Penteado, João C.T. [UNESP], Gaspar, Roberta C. [UNESP]   +25 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Cumulus co-culture system does not improve the in-vitro maturation (IVM) of oocytes in mice

Middle East Fertility Society Journal, 2016
Objective: To examine the effect of co-culture system with CCs on the in vitro maturation (IVM) of immature oocytes retrieved from mice. Design: This is an experimental study. Setting: Research and Clinical Center for Infertility of Yazd. Sample: A total
Tahereh Rahiminia, Azita Faramarzi, Arezoo Khoradmehr, Mohammad Ali Khalili   +3 more
doaj   +1 more source