Results 91 to 100 of about 640,334 (311)

Cumulus co-culture system does not improve the in-vitro maturation (IVM) of oocytes in mice

Middle East Fertility Society Journal, 2016
Objective: To examine the effect of co-culture system with CCs on the in vitro maturation (IVM) of immature oocytes retrieved from mice. Design: This is an experimental study. Setting: Research and Clinical Center for Infertility of Yazd. Sample: A total
Tahereh Rahiminia, Azita Faramarzi, Arezoo Khoradmehr, Mohammad Ali Khalili   +3 more
doaj   +1 more source

Dendritic-Cell (DC)-Based Immunotherapy: Tumor Endothelial Marker 8 (TEM8) Gene Expression of DC Vaccines Correlates with Clinical Outcome [PDF]

, 2008
\ud Previous studies have shown that tumor-endothelial markers (TEMs) are upregulated in immunosuppressive, pro-angiogenic dendritic cells (DCs) found in tumor microenvironments. \ud We reported that pro-angiogenic monocyte-derived DCs (Mo-DCs), utilized
Bolli, Elisabetta, Ridolfi, R., Venanzi, F.M.   +2 more
core  

Fat area and lipid droplet morphology of porcine oocytes during in vitro maturation with trans-10, cis-12 conjugated linoleic acid and forskolin [PDF]

, 2012
Lipid droplets (LD) in porcine oocytes form a dark mass reaching almost all cytoplasm. Herein we investigated changes in fat areas, cytoplasmic tone and LD morphology during in vitro maturation (IVM) of porcine oocytes cultured with 100mM trans-10, cis ...
Baptista, MC, Carolino, N, Charneca, R, Horta, AEM, Marques, CC, Nunes, JT, Pereira, RM, Prates, EG, Vasques, MI   +8 more
core   +2 more sources

Biphasic in-vitro maturation: an advancement over traditional in-vitro maturation

MedPharmRes
Culture conditions for standard in-vitro maturation (IVM) have remained largely unchanged for more than 50 years and are non-physiological, limiting the success of this form of assisted reproductive technology (ART).
Lan N Vuong, Tuong M Ho, Robert B. Gilchrist   +2 more
openaire   +1 more source

In-vitro maturation of human oocytes

Reproductive BioMedicine Online, 2004
Immature human oocytes can be matured and fertilized in vitro. However, subsequent embryonic development is different when the immature oocytes are retrieved in different situations. Exposure to the LH surge in vivo may be important for the oocytes to acquire the competence for maturation and subsequent embryonic development.
Ri-Cheng, Chian, William M, Buckett, Seang-Lin, Tan   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Live birth after rescue in vitro maturation–intracytoplasmic sperm injection in type 1 diabetes, polycystic ovary syndrome patient using clomiphene–antagonist protocol

Journal of Human Reproductive Sciences, 2018
Infertility in patients with polycystic ovary syndrome (PCOS) associated with diabetes leads to challenging situations seeking alternative treatments.
Samundi Sankari, M Elanchezhian, Divya Selvamani, M Nagarajan, D Gopikrishnan   +4 more
doaj   +1 more source

Polyunsaturated fatty acids influence offspring sex ratio in cows [PDF]

, 2018
Dietary polyunsaturated fatty acids (PUFAs) can influence fertility in farm animals. Some evidence in mice and sheep have suggested that PUFAs may influence offspring sex ratio, which may have significant value for cattle production.
Abo El-Atta, A M A, El-Harairy, M A, Fouladi-Nashta, A A, Khalil, W A, Marei, W F A, Pushpakumara, P G A, Wathes, D C   +6 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Influence of N-acetyl-L-cysteine against bisphenol a on the maturation of mouse oocytes and embryo development: in vitro study

BMC Pharmacology and Toxicology, 2019
Background Bisphenol A (BPA), an endocrine disruptor, is a widely used chemical that has adverse effects on animal development and reproduction. The current research aimed to evaluate the effect of BPA on the in vitro maturation (IVM) and subsequent ...
Qian Li, Zhenjun Zhao
doaj   +1 more source