Results 71 to 80 of about 114,426,039 (308)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ovarian and follicular culture enables the production of fertile oocytes in C57BL/6 mice
The Journal of Reproduction and DevelopmentIn vitro experiments have become a powerful alternative to in vivo approaches for analyzing gene functions and molecular mechanisms.
Kyota YOSHIDA +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Control of gonad growth, maturation and spawning in teleost fish: A review [PDF]
, 1996 Despite their great variety of reproductive strategies, a general characteristic of most teleosts is that (where known) natural reproduction shows a long-term periodicity, even in tropical habitats (e.g. see contributions in Munro et al.
Lam, Tom J., Munro, Angus D.
core +1 more source
In vitro blastocyst development of post-thaw vitrified bovine oocytes [PDF]
Veterinary World, 2013 Aim: To evaluate the developmental competence of post-thaw vitrified bovine cumulus-oocyte complexes (COCs) in vitro.Materials and Methods: A total of 129 COCs were cryopreserved using vitrification solution comprising of 15% ethylene glycol (EG) + 15 ...
D. J. Dutta, +2 more
doaj +1 more source
In vitro maturation of canine oocyte [PDF]
, 2005 Compared to other mammals, the canine oocyte offers a very unusual model of meiosis. Its maturation in vitro, studied only over the past ten years, is still poorly controlled: low rate of metaphase II (10 to 20% vs. over 90% in cattle),
REYNAUD, Karine +9 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Biphasic in-vitro maturation: an advancement over traditional in-vitro maturation
MedPharmResCulture conditions for standard in-vitro maturation (IVM) have remained largely unchanged for more than 50 years and are non-physiological, limiting the success of this form of assisted reproductive technology (ART).
Lan N Vuong +2 more
openaire +1 more source
Activation of proteolysis during oocyte in vitro maturation [PDF]
In vitro maturation (IVM) is a form of assisted reproductive technology (ART) applied to obtain mature oocytes in culture. Decline in IVM success rates by age has led consideration of novel approaches based on cellular dynamics.
Bulut, Berk +5 more
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Adjuvance of influenza virosomes in CTL induction in vitro [PDF]
, 2005 The induction of cytotoxic T lymphocyte (CTL) responses is of high relevance in immunological defense against intracellular pathogens and tumor cells.
Schumacher, Reto
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