Results 61 to 70 of about 114,426,039 (308)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Quercetin Efficacy on in vitro Maturation of Porcine Oocytes

Scientific Papers Animal Science and Biotechnologies, 2023
The present study proposed to examine the effects of a polyphenol (quercetin) on in vitro maturated parameters. Quercetin it has been extensively studied by researchers on animals over the 35 years.
Delia Orlovschi, Ileana Miclea, Marius Zahan, Vasile Miclea, Anamaria Pernes   +4 more
doaj  

EFFECT OF CYSTEAMINE ON THE RATE OF IN VITRO MATURATION OF OOCYTES IN TWO MEDIA [PDF]

Acta Medica Iranica, 2006
Rate of in vitro maturation of oocytes is one of the challenges of assisted reproductive techniques. In this study we investigated the effects of supplementation of cysteamine on the rate of in vitro maturation of oocytes in two different media. Germinal
A. Mohammadi-Rousheh, M. H. Noori-Mooghahi, P. Pasbakhsh, A. Abddvahabi, M. Akbari, A. Shokrgozar A. Sobhani   +5 more
doaj   +1 more source

Ovarian morphometric characterization and in vitro maturation of oocytes obtained from buffalo (Bubalus bubalis) ovaries – partial results

Italian Journal of Animal Science, 2010
Buffalo ovaries were collected from a slaughterhouse (Frigol, Brazil) and transported to the laboratory in saline solution at 36º C. The ovaries were dissected to realize the evaluations (weight, length, width and height of the ovary; corpus luteum ...
F.C. Landim-Alvarenga, L.R. Martins, I. Martin, C.F. Moya, C.B. Fernandes, L.S. Leal, E. Oba   +6 more
doaj   +1 more source

Human TIMP1 Is a Growth Factor That Improves Oocyte Developmental Competence

BioTech, 2023
Oocyte developmental competence is the ability of a mature oocyte to be fertilized and subsequently support embryonic development. Such competence is gained during folliculogenesis and is facilitated by the bidirectional communication into a compacted ...
Yolanda Manríquez-Treviño, Blanca Sánchez-Ramírez, Juan Alberto Grado-Ahuir, Beatriz Castro-Valenzuela, Carmen González-Horta, M.Eduviges Burrola-Barraza   +5 more
doaj   +1 more source

in Vitro Maturation of Human Oocytes

Taiwanese Journal of Obstetrics and Gynecology, 2006
Immature oocyte retrieval followed by in vitro maturation (IVM) opens a new horizon for modern assisted reproductive technologies (ART). Recent studies in IVM make it a feasible alternative to in vitro fertilization. Antral follicle count is correlated with the pregnancy rate, so women with polycystic ovarian syndrome or polycystic ovaries are the best
Yu-Hung Lin, Jiann-Loung Hwang
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Optimal Allogeneic Platelet-Rich Plasma Concentration to Improve In Vitro Maturation of Germinal Vesicle Oocytes From Women With Polyendocrine Metabolic Ovarian Syndrome: A Prospective Cohort Study

Clinical and Experimental Obstetrics & Gynecology
Background:In vitro maturation is a long-established technique used to obtain mature oocytes outside the human body. As an alternative to assisted reproductive technology (ART) protocols involving controlled ovarian stimulation (COS) followed by in vitro
Tiara Kusumaningtyas, Ita Fauzia Hanoum, Rr Vicki Nuri Prijayanti, Diany Ayu Suryaningtyas, Annisa Nur Islahi, Naila Nabila Rahmani, Intan Kusumaningtyas, Berli Kusuma, Anto Sawarno, Dewi Kartikawati Paramita, Djaswadi Dasuki   +10 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Expression of genes associated with BMP signaling pathway in porcine oocytes before and after IVM – a microarray approach

Reproductive Biology and Endocrinology, 2017
Background The full maturational capability of mammalian oocytes is accompanied by nuclear and cytoplasmic modifications, which are associated with proliferation and differentiation of surrounding cumulus cells.
Joanna Budna, Marta Rybska, Sylwia Ciesiółka, Artur Bryja, Sylwia Borys, Wiesława Kranc, Katarzyna Wojtanowicz-Markiewicz, Michal Jeseta, Ewa Sumelka, Dorota Bukowska, Paweł Antosik, Klaus P. Brüssow, Małgorzata Bruska, Michał Nowicki, Maciej Zabel, Bartosz Kempisty   +15 more
doaj   +1 more source