Results 221 to 230 of about 701,007 (399)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Rates and risk factors of oocyte immaturity: toward personalized selection for rescue in vitro maturation. [PDF]

J Assist Reprod Genet
Taggi M, Maggiulli R, Innocenti F, Casciani V, Cermisoni GC, Soscia DM, Petrone P, Ruffa A, Albricci L, Fiorentino G, Zuccotti M, Vaiarelli A, Capalbo A, Coticchio G, Rienzi L, Cimadomo D.   +15 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Advances in human oocyte in vitro maturation: current status and future perspectives: a narrative review. [PDF]

Reprod Fertil
Liu M, Cui J, Chang HM, Liu J, Leung PCK.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Rescue In Vitro Maturation of a Germinal Vesicle Oocyte Leading to Pregnancy in a Case of Unexplained Infertility. [PDF]

Cureus
Akbari EA, Khrait Z, Kondakova N, Eaton S.   +3 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Indole-3-propionic acid supplementation during in vitro maturation improves in vitro production of porcine embryos. [PDF]

BMC Vet Res
Nakayama Y, Otoi T, Zhao N, Nguyen ST, Torigoe N, Lin Q, Bin L, Widodo OS, Tharasanit T, Chatdarong K, Hirata M, Nagahara M, Tanihara F.   +12 more
europepmc   +1 more source

In vitro pituitary prolactin, growth hormone and follicle stimulating hormone secretion during sexual maturation of female rats primed with melatonin

, 2001
Elena Dı́az, C Fernández Alvarez, Patricia O. Castrillón, Ana I. Esquifino, B Dı́az López   +4 more
openalex   +2 more sources

Altered expression of Armet and Mrlp51 in the oocyte, preimplantation embryo, and brain of mice following oocyte in vitro maturation but postnatal brain development and cognitive function are normal [PDF]

, 2011
Ning Wang, Liya Wang, Le Fang, Qitao Zhan, Yingming Zheng, Guolian Ding, Xijing Chen, Jian‐Zhong Sheng, Minyue Dong, He-feng Huang, Fan Jin   +10 more
openalex   +1 more source