Results 251 to 260 of about 397,646 (312)

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

In Vitro Maturation, In Vitro Oogenesis, and Ovarian Longevity. [PDF]

Reprod Sci
Silber SJ, Goldsmith S, Castleman L, Hayashi K.   +3 more
europepmc   +1 more source

In Vitro Maturation of Bovine Oocytes and Recent Innovations by Harnessing the Power of Diverse Antioxidants [PDF]

Mona A. Mahmoud, Abdeltawab Abdelrazik Yassin, Bakar Ramadan Abdelhaim, El-sayed Mahmoud Abdelgwad, Rabie L. Abdel Aziz   +4 more
openalex   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Overcoming PCOS-Related Infertility by Using In Vitro Maturation Approach: A Case Report. [PDF]

Cureus
Jain A, Bawaskar PA, Nair N, Kalbande A, Pareek C.   +4 more
europepmc   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Optimizing <i>in vitro</i> maturation of oocytes with nitric oxide-loaded microbubbles. [PDF]

Front Cell Dev Biol
Qiu L, Xu Q, Lin Y, Wang S, Zhang H, Liu Y, Zhao J, Zhao Y, Xi H.   +8 more
europepmc   +1 more source

Ultrastructural Characteristics of Mouse Preantral Follicles Isolated from Vitrified and Non Vitrified Ovaries after In Vitro Maturation

, 2007
Heydari Kamran, Mojdeh Salehnia, M Rezazadeh Valoujerdi   +2 more
openalex   +1 more source

Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro

Advanced Biology, EarlyView.
Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Grossi Alice, Fulghieri Paola, Aduvaliev Abdurakhmon, Soffiantini Karen, Oldrati Irene, Cavallo Margherita, Biggiogera Marco, Pellavio Giorgia, Laforenza Umberto, Savio Monica, Sottile Virginie   +10 more
wiley   +1 more source

Testing the role of unstimulated in vitro maturation for potential development of immature oocytes in women with oocyte maturation abnormalities [PDF]

J Turk Ger Gynecol Assoc
Kalyoncu Ş, Başbuğ A, Hatırnaz E, Ellibeş Kaya A, Dokuzeylül Güngör N, Ürkmez SS, Civil Ürkmez Y, Hatırnaz Ş.   +7 more
europepmc   +1 more source