Results 71 to 80 of about 117,927,284 (283)

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

Episode 83: In Vitro Meat with Josh Milburn

open access: yes, 2018
In this episode of Knowing Animals I am joined by Josh Milburn. Josh is Associate Lecturer in Political Philosophy at the University of York. We will discuss Josh’s article ‘Chewing Over In Vitro Meat: Animal Ethics, Cannibalism and Social Progress ...
Milburn, Josh, O'Sullivan, Siobhan
core  

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

open access: yesAdvanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu   +10 more
wiley   +1 more source

A new and sustainable alternative food product: willingness to pay for cultured beef

open access: yesFrontiers in Sustainable Food Systems
This study aimed to identify consumers in Türkiye's attitudes toward consuming cultured beef, a new and sustainable food product, their willingness to pay, and the factors influencing these consumption.
Gokhan Cinar, Sidika Bozkiran Yilmaz
doaj   +1 more source

The Studies on Embryo Production from Hanwoo Cows with High Offspring Meat Quality Grade and Embryo Transfer

open access: yesJournal of Animal Reproduction and Biotechnology, 2019
These studies were conducted to evaluate developmental competence of follicular oocyte collected from the ovaries of Hanwoo cows with the high offspring meat quality (1++ and 1+ grade).
Hae-Lee Lee   +3 more
doaj   +1 more source

AI‐Powered, Temperature‐Resolved Centrifugal Microfluidics for Rapid 3D Phase‐Diagram Generation of Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li   +6 more
wiley   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

open access: yesAdvanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka   +10 more
wiley   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

open access: yesAdvanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling   +18 more
wiley   +1 more source

Tissue engineering approaches to develop cultured meat from cells: A mini review

open access: yesCogent Food & Agriculture, 2017
Cultured meat production is an innovative and emerging process to produce animal meat in laboratories, using tissue-engineering techniques. This novel approach to produce meat involves in vitro culture of the animal muscle tissues rather than rearing ...
Muhammad Sajid Arshad   +5 more
doaj   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

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