Results 221 to 230 of about 117,927,284 (283)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Simultaneous T1 and T2 Mapping in the Brain With QuantoRAGE: An MP2RAGE Variant Using T2‐Prepared Inversion

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and validate a repeatable and reproducible approach, QuantoRAGE, for simultaneous whole‐brain T1 and T2 mapping using adiabatic magnetization preparation. Methods QuantoRAGE is a 3D FLASH‐based sequence using an adiabatic T2‐prepared inversion followed by two readout blocks.
Natalia Pato Montemayor, Tâm Johan Nguyên, José P. Marques, Berk Can Açikgöz, Jessica A. M. Bastiaansen, Roland Kreis, Piotr Radojewski, Jonathan Stelter, Dimitrios Karampinos, Jocelyn Philippe, Lina Bacha, Tommaso Di Noto, Bénédicte Maréchal, Dominik Nickel, Patrick A. Liebig, Robin M. Heidemann, Tobias Kober, Jean‐Philippe Thiran, Tom Hilbert, Thomas Yu, Gian Franco Piredda, Gabriele Bonanno   +21 more
wiley   +1 more source

Health Risk Assessment of Dietary Arsenic Exposure and Selenium Deficiency in Tibet Based on In Vitro Gastrointestinal Simulation. [PDF]

ACS Omega
Sun J, Yu H, Chai L, Wang X, Zhang R, Zhou Y, Dong H, Gong P.   +7 more
europepmc   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

The Hidden Burden of Water-Binding Additives in Meat Products: Biochemical, Clinical, and Psychosocial Implications. [PDF]

Mol Nutr Food Res
Kamyshnyi O, Halabitska I, Bjorås M, Sæther IB, Brautaset T, Kamyshna I, Lushchak O, Oksenych V, Petakh P, Kainov DE.   +9 more
europepmc   +1 more source

Chemical diversity and phylogenetic insights into Hawaiian ʻākia (Wikstroemia) species used in traditional fishing practices

PLANTS, PEOPLE, PLANET, EarlyView.
Traditional fishing with plant‐based piscicides is a global practice in decline, facing increasing restrictions. We investigated the chemical diversity of endemic Wikstroemia species historically used to stun or poison fish in Hawaiʻi. Using 1‐H‐NMR, principal component analysis, targeted HPLC, and target‐capture sequencing, we characterized compounds ...
Louise Winther, Isaac Lichter‐Marck, Louise Kjaerulff, David Lorence, Uma Nagendra, Mike Opgenorth, Sverre J. Schou, Kenneth R. Wood, Felipe Zapata, Dan Staerk, Nina Rønsted   +10 more
wiley   +1 more source

Milk-derived peptone reduces EHEC virulence by inhibiting the type III secretion system. [PDF]

Virulence
Braverman D, Batushansky A, Sal-Man N.
europepmc   +1 more source

Biocontrol and plant growth‐promoting potential of Streptomyces strains against fungal pathogens of tomato and wheat for a sustainable agriculture

Pest Management Science, EarlyView.
This study highlights the biocontrol potential of Streptomyces strain Strep_22. In vitro, it inhibits key fungal pathogens by 91.52%. In vivo, it significantly reduces disease incidence in wheat and tomato while enhancing biomass, shoot, and root development, offering a highly promising, sustainable ecological alternative to chemical pesticides ...
Thomas Conte, Maria Grazia Morea, Gaetana Ricciardi, Angelo Pastino, Francesco Lops, Maria Luisa Raimondo, Antonia Carlucci   +6 more
wiley   +1 more source

Valorisation of Prosciutto di Parma PDO by-products for the development of protein-rich snacks. [PDF]

Front Nutr
Rossi F, Cassarino M, Valoti P, Dall'Olio G, Fornari E, Giuberti G, Rocchetti G, Zampieri I, Leni G, Dall'Asta M.   +9 more
europepmc   +1 more source

Oral RNAi reduces survival and grain loss in Rhyzopertha dominica, including phosphine‐resistant populations

Pest Management Science, EarlyView.
Oral delivery of dsRNA targeting essential genes reduces adult survival and grain damage in Rhyzopertha dominica, including highly phosphine‐resistant populations. These findings support RNAi as a complementary mode‐of‐action for resistance management and postharvest protection in stored‐grain systems. Abstract BACKGROUND Phosphine fumigation remains a
ZiHan Shen, Wei Chen, KangXu Wang
wiley   +1 more source