Results 21 to 30 of about 1,720,158 (168)
A modular in vitro flow model to analyse blood-surface interactions under physiological conditions
Current Directions in Biomedical Engineering, 2021 Newly developed materials for blood-contacting devices need to undergo hemocompatibility testing to prove compliance with clinical requirements. However, many current in vitro models disregard the influence of flow conditions and blood exchange as it ...
Valtin Juliane +5 more
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Two-Step In Vitro Model to Evaluate the Cellular Immune Response to SARS-CoV-2
Cells, 2021 The cellular immune response plays an important role in COVID-19, caused by SARS-CoV-2. This feature makes use of in vitro models’ useful tools to evaluate vaccines and biopharmaceutical effects.
Juliana G. Melgaço +25 more
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In vitro models of axon regeneration [PDF]
Experimental Neurology, 2017 A variety of in vitro models have been developed to understand the mechanisms underlying the regenerative failure of central nervous system (CNS) axons, and to guide pre-clinical development of regeneration-promoting therapeutics. These range from single-cell based assays that typically focus on molecular mechanisms to organotypic assays that aim to ...
Hassan, Al-Ali +3 more
openaire +2 more sources
Frontiers in Oncology, 2017 Over the past decade, the development of new targeted therapeutics directed against specific molecular pathways involved in tumor cell proliferation and survival has allowed an essential improvement in carcinoma treatment.
Manuela Gaebler +8 more
doaj +1 more source
Tumor models in the investigation of oral cancer pathogenesis and treatment development
RUDN Journal of MedicineRelevance. Oral cancer is one of the most common cancers among neoplasms of the head and neck. Oral cancer is characterized by a poor prognosis, a lack of specific biomarkers and highly effective targeted treatment.
Maria S. Tretyakova +4 more
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What Do In Vitro and In Vivo Models Tell Us about Anisakiasis? New Tools Still to Be Explored
Pathogens, 2022 Anisakiasis is a zoonosis caused by the ingestion of raw or undercooked seafood infected with third-stage larvae (L3) of the marine nematode Anisakis.
Serena Cavallero +3 more
doaj +1 more source
Nanomaterials, 2017 : Fine/micron-sized iron oxide particulates are incidentally released from a number of industrial processes, including iron ore mining, steel processing, welding, and pyrite production.
Tiffany G. Kornberg +6 more
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3D Printing of Organs-On-Chips
Bioengineering, 2017 Organ-on-a-chip engineering aims to create artificial living organs that mimic the complex and physiological responses of real organs, in order to test drugs by precisely manipulating the cells and their microenvironments. To achieve this, the artificial
Hee-Gyeong Yi +2 more
doaj +1 more source
Pharmaceutics, 2022 (1) Background: Sutures with triclosan (TS) are used to reduce the risk of surgical site infections (SSI), but most clinical trials are inconclusive. The traceability of SSI risk to antimicrobial activity in operated tissues is needed.
Frederic Christopher Daoud +2 more
doaj +1 more source
Bioengineering, 2021 Age-related macular degeneration (AMD) is the leading cause of vision loss in the elderly worldwide. So far, the etiology and the progression of AMD are not well known.
Beatrice Belgio +2 more
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