Results 31 to 40 of about 2,928,750 (309)

Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]

, 2014
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Adams, Beciani, Bhayana, Boulier, Collinson, Collinson, Collinson, Conway, Deegan, Donnino, Frankel, Hickman, Katrukha, Keller, Khan, Krummel, Lippi, Lowbeer, Mockel, Morrow, Muller-Bardorff, Orea-Tejeda, Peetz, Reichlin, Sahinarslan, Sharma, Sommerer, Stoffel, Tarakcioglu, Thygesen, Tomisawa, Wang, Wayand   +32 more
core   +1 more source

In vitro models of axon regeneration [PDF]

Experimental Neurology, 2017
A variety of in vitro models have been developed to understand the mechanisms underlying the regenerative failure of central nervous system (CNS) axons, and to guide pre-clinical development of regeneration-promoting therapeutics. These range from single-cell based assays that typically focus on molecular mechanisms to organotypic assays that aim to ...
Hassan, Al-Ali, Samuel R, Beckerman, John L, Bixby, Vance P, Lemmon   +3 more
openaire   +2 more sources

Three-Dimensional Patient-Derived In Vitro Sarcoma Models: Promising Tools for Improving Clinical Tumor Management

Frontiers in Oncology, 2017
Over the past decade, the development of new targeted therapeutics directed against specific molecular pathways involved in tumor cell proliferation and survival has allowed an essential improvement in carcinoma treatment.
Manuela Gaebler, Alessandra Silvestri, Johannes Haybaeck, Johannes Haybaeck, Peter Reichardt, Caitlin D. Lowery, Louis F. Stancato, Gabriele Zybarth, Christian R. A. Regenbrecht   +8 more
doaj   +1 more source

Tumor models in the investigation of oral cancer pathogenesis and treatment development

RUDN Journal of Medicine
Relevance. Oral cancer is one of the most common cancers among neoplasms of the head and neck. Oral cancer is characterized by a poor prognosis, a lack of specific biomarkers and highly effective targeted treatment.
Maria S. Tretyakova, Elizaveta A. Prostakishina, Elena S. Kolegova, Evgeny L. Choinzonov, Evgeny V. Denisov   +4 more
doaj   +1 more source

Rate-controlled rectal drug delivery in man with a hydrogel preparation [PDF]

, 1986
Cylindrical hydrogels of hydroxyethyl methacrylate (HEMA) and ethylene glycol dimethacrylate (EGDMA) as crosslinking agent were prepared by radical polymerization at 70°C.
Boer, A.G. de, Breimer, D.D., Feijen, J., Leede, L.G.J. de, Pörtzgen, E.   +4 more
core   +3 more sources

What Do In Vitro and In Vivo Models Tell Us about Anisakiasis? New Tools Still to Be Explored

Pathogens, 2022
Anisakiasis is a zoonosis caused by the ingestion of raw or undercooked seafood infected with third-stage larvae (L3) of the marine nematode Anisakis.
Serena Cavallero, Ilaria Bellini, Antonella Pizzarelli, Stefano D’Amelio   +3 more
doaj   +1 more source

Potential Toxicity and Underlying Mechanisms Associated with Pulmonary Exposure to Iron Oxide Nanoparticles: Conflicting Literature and Unclear Risk

Nanomaterials, 2017
: Fine/micron-sized iron oxide particulates are incidentally released from a number of industrial processes, including iron ore mining, steel processing, welding, and pyrite production.
Tiffany G. Kornberg, Todd A. Stueckle, James A. Antonini, Yon Rojanasakul, Vincent Castranova, Yong Yang, Liying Wang   +6 more
doaj   +1 more source

ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. [PDF]

, 2018
BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation ...
Fu, Z, Hu, Q, Ke, X, Li, P, Liu, Y, Sun, J, Tan, Z, Wang, H, Zhang, W, Zhang, Y, Zheng, C, Zheng, Z   +11 more
core   +1 more source

3D Printing of Organs-On-Chips

Bioengineering, 2017
Organ-on-a-chip engineering aims to create artificial living organs that mimic the complex and physiological responses of real organs, in order to test drugs by precisely manipulating the cells and their microenvironments. To achieve this, the artificial
Hee-Gyeong Yi, Hyungseok Lee, Dong-Woo Cho   +2 more
doaj   +1 more source

Dental erosion: In vitro model of wine assessor's erosion [PDF]

, 2001
The document attached has been archived with permission from the Australian Dental Association. An external link to the publisher’s copy is included.Background: Wine makers and assessors frequently experience severe dental erosion. The objectives of this
Hunt, D., McIntyre, J., Mok, T.
core   +2 more sources