Results 21 to 30 of about 1,760,692 (269)
An In Vitro Model of Glioma Development
Genes, 2023 Gliomas are the prevalent forms of brain cancer and derive from glial cells. Among them, astrocytomas are the most frequent. Astrocytes are fundamental for most brain functions, as they contribute to neuronal metabolism and neurotransmission. When they acquire cancer properties, their functions are altered, and, in addition, they start invading the ...
Gabriella Schiera +14 more
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Two-Step In Vitro Model to Evaluate the Cellular Immune Response to SARS-CoV-2
Cells, 2021 The cellular immune response plays an important role in COVID-19, caused by SARS-CoV-2. This feature makes use of in vitro models’ useful tools to evaluate vaccines and biopharmaceutical effects.
Juliana G. Melgaço +25 more
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A modular in vitro flow model to analyse blood-surface interactions under physiological conditions
Current Directions in Biomedical Engineering, 2021 Newly developed materials for blood-contacting devices need to undergo hemocompatibility testing to prove compliance with clinical requirements. However, many current in vitro models disregard the influence of flow conditions and blood exchange as it ...
Valtin Juliane +5 more
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An In Vitro Model for Thyroid Autoimmunity [PDF]
, 1987 Clinical observations have suggested an association between iodine intake and the occurance of autoimmune thyroiditis in man (1,2), while in areas with endemic goiter prevalence due to iodine deficiency a lower incident of Hashimoto’s thyroditis was found (3), Others, however, have contested these claims (4,5). Experimentally, this association has been
Wenzel, B. E. +3 more
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Frontiers in Oncology, 2017 Over the past decade, the development of new targeted therapeutics directed against specific molecular pathways involved in tumor cell proliferation and survival has allowed an essential improvement in carcinoma treatment.
Manuela Gaebler +8 more
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Tumor models in the investigation of oral cancer pathogenesis and treatment development
RUDN Journal of MedicineRelevance. Oral cancer is one of the most common cancers among neoplasms of the head and neck. Oral cancer is characterized by a poor prognosis, a lack of specific biomarkers and highly effective targeted treatment.
Maria S. Tretyakova +4 more
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What Do In Vitro and In Vivo Models Tell Us about Anisakiasis? New Tools Still to Be Explored
Pathogens, 2022 Anisakiasis is a zoonosis caused by the ingestion of raw or undercooked seafood infected with third-stage larvae (L3) of the marine nematode Anisakis.
Serena Cavallero +3 more
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In Vitro Microscale Models for Embryogenesis
Advanced Biosystems, 2018 AbstractEmbryogenesis is a highly regulated developmental process requiring complex mechanical and biochemical microenvironments to give rise to a fully developed and functional embryo. Significant efforts are taken to recapitulate specific features of embryogenesis by presenting the cells with developmentally relevant signals.
Jennifer Rico‐Varela +2 more
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Nanomaterials, 2017 : Fine/micron-sized iron oxide particulates are incidentally released from a number of industrial processes, including iron ore mining, steel processing, welding, and pyrite production.
Tiffany G. Kornberg +6 more
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In vitro models for investigating itch
Frontiers in Molecular Neuroscience, 2022 Itch (pruritus) is a sensation that drives a desire to scratch, a behavior observed in many animals. Although generally short-lasting and not causing harm, there are several pathological conditions where chronic itch is a hallmark symptom and in which prolonged scratching can induce damage.
Hendrik Mießner +3 more
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