Results 141 to 150 of about 1,346,069 (268)

Preclinical Models of Atopic Dermatitis Suitable for Mechanistic and Therapeutic Investigations

Journal of Inflammation Research
Anish R Maskey,1 Xian Mo,1,2 Xiu-Min Li1,3,4 1Department of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, 10595, USA; 2The Department of Allergy and Clinical Immunology, Guangzhou Institute of Respiratory Health ...
Maskey AR, Mo X, Li XM
doaj  

In vitro models for testicular steroidogenesis: current status and future perspectives. [PDF]

Arch Toxicol
Řehůřková E, Bajard L, Sovadinová I.   +2 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

The Effects of Neurotropic B Vitamins, Vitamin D3, and Alpha-Lipoic Acid in In Vitro Models of Neurodegeneration. [PDF]

Nutrients
Viel C, Shi Y, Trueman RP, Ruiz AJ, Rayner MLD.   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The vertebrate yolk sac: evolutionary origins and current advances in in vitro models. [PDF]

Development
Blagrove JR, Orsi AER, Cindrova-Davies T, Niakan KK.   +3 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Nanomaterial toxicity and risk assessment integrating functionalization strategies advanced in vitro models and regulatory perspectives. [PDF]

Discov Nano
Patel J, Roy H, Khobragade DS, Das NR, Patel R, Lal P, Maddina B, Bohara R.   +7 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Comments on 'Bisphosphonate and statin: adverse effects of co-medication on wound healing in in vitro models of periodontal tissues'. [PDF]

Acta Odontol Scand
Szaraz D, Perina V, Borilova Linhartova P.   +2 more
europepmc   +1 more source