Results 1 to 10 of about 5,848,146 (301)

Effects of Autophagy-related Genes and Signal Pathways on Occurrence and Development of Oral Tumors

Zhongliu Fangzhi Yanjiu, 2021
Autophagy is a highly conservative cellular self-protective behavior dependent on lysosomes, and can be used as an important factor in promoting or preventing cancer, and its effect is related to the type and development of tumors.
XUE Rui, GAO Jiping, YAN Xiaoru, XU Guoqiang, SONG Guohua   +4 more
doaj   +1 more source

Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

Scientific Reports, 2022
Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...
Valeriia Bondarenko, Cecillie Reynolds Løkke, Peter Dobrowolski, Caroline Junker Mentzel, Josué L. Castro-Mejía, Camilla Hartmann Friis Hansen, Dorte Bratbo Sørensen, Dennis Sandris Nielsen, Lukasz Krych, Axel Kornerup Hansen   +9 more
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Advantages and Progress of Using Chinese Hamsters to Construct Disease Models

Shiyan dongwu yu bijiao yixue, 2021
Chinese hamsters are experimental animals originally from China. They play an important role in experimental research on medicine and biology. They are widely used in life science research, such as genetics, infectious diseases, tissue culture ...
GAO Jiping, CHEN Zhaoyang, XUAN Ruijing, ZHANG Ruihu, SONG Guohua   +4 more
doaj   +1 more source

Preliminary study on the efficacy of rituximab in the treatment of idiopathic membranous nephropathy: A single-centre experience

Frontiers in Endocrinology, 2023
ObjectiveTo investigate the efficacy of rituximab in the treatment of idiopathic membranous nephropathy (IMN).MethodsA total of 77 patients with IMN diagnosed in both our hospital and other hospitals were included in this study; the patients were divided
Ping Chen, Ping Chen, Min Mao, Min Mao, Chendan Wang, Chendan Wang, Xu Zhang, Xu Zhang, Xiaoyu Zhao, Xiaoyu Zhao, Yuanyuan Gao, Yankun Luo, Yankun Luo, Yun Zhou, Yun Zhou, Yun Zhou   +15 more
doaj   +1 more source

Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

Antioxidants, 2022
Vitamin C (vitC) deficiency has been associated with an increased risk of cardiovascular disease; while several putative mechanistic links have been proposed, functional evidence supporting a causal relationship is scarce.
Gry Freja Skovsted, Josephine Skat-Rørdam, Amalie Pihl Frøkiær, Henrik Elvang Jensen, Pernille Tveden-Nyborg, Jens Lykkesfeldt   +5 more
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Optimal experimental design for mathematical models of haematopoiesis. [PDF]

, 2021
The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells.
Iniguez, Abdon, Jena, Nilamani, Lander, Arthur D, Liu, Zhong-Ying, Lomeli, Luis Martinez, Lowengrub, John S, Minin, Vladimir N, Shahbaba, Babak, Tata, Prasanthi, Van Etten, Richard   +9 more
core   +1 more source

Heterozygous lipoprotein lipase knockout mice exhibit impaired hematopoietic stem/progenitor cell compartment

Animal Models and Experimental Medicine, 2021
Background Hematopoietic stem cells (HSC) maintain the hematopoietic system homeostasis through self‐renewal and multilineage differentiation potential. HSC are regulated by the microenvironment, cytokine signaling, and transcription factors.
Guiying Shi, Xinyue Li, Keya Li, Yiying Huang, Xuepei Lei, Lin Bai, Chuan Qin   +6 more
doaj   +1 more source

Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig

Antioxidants, 2021
Oxidative stress is directly linked to non-alcoholic fatty liver disease (NAFLD) and the progression to steaotohepatitis (NASH). Thus, a beneficial role of antioxidants in delaying disease progression and/or accelerating recovery may be expected, as ...
Josephine Skat-Rørdam, Kamilla Pedersen, Gry Freja Skovsted, Ida Gregersen, Sara Vangsgaard, David H. Ipsen, Markus Latta, Jens Lykkesfeldt, Pernille Tveden-Nyborg   +8 more
doaj   +1 more source

Acute immune responses in zebrafish and evasive behavior of a parasite – who is winning?

Frontiers in Cellular and Infection Microbiology, 2023
The protozoan parasite Ichthyophthirius multifiliis is an economically important parasite for the aquaculture- and ornamental fish industry. The parasite is abundant worldwide and infects the skin, gills and fins of freshwater fish species.
Heidi Mathiessen, Sebastian Kjeldgaard-Nintemann, Carlota Marola Fernandez Gonzalez, Cyril Henard, Julie Algreen Reimer, Sara Vebæk Gelskov, Moonika Haahr Marana, Louise von Gersdorff Jørgensen   +7 more
doaj   +1 more source

Delayed Gut Colonization Shapes Future Allergic Responses in a Murine Model of Atopic Dermatitis

Frontiers in Immunology, 2021
Epidemiological studies have long reported that perturbations of the childhood microbiome increase the risk of developing allergies, but a causal relationship with atopic dermatitis remains unclear.
Amalie W. Arildsen, Line F. Zachariassen, Lukasz Krych, Axel K. Hansen, Camilla H. F. Hansen   +4 more
doaj   +1 more source