Results 11 to 20 of about 2,204,686 (267)

Experimental Models of Dermatophytosis [PDF]

, 2021
Dermatophytosis is a superficial fungal infection of the keratinized structures of the host. Since the last decade, this mycosis became an important health concern due to an increasing prevalence and to the limited number and efficacy of available treatments.
Faway, Emilie, Thiry, Marc, Mignon, Bernard, Poumay, Yves   +3 more
openaire   +3 more sources

Neuroprotective Effects of Ceftriaxone Involve the Reduction of Aβ Burden and Neuroinflammatory Response in a Mouse Model of Alzheimer’s Disease

Frontiers in Neuroscience, 2021
Ceftriaxone (CEF) is a safe and multipotent antimicrobial agent that possesses neuroprotective properties. Earlier, we revealed the restoration of cognitive function in OXYS rats with signs of Alzheimer’s disease (AD)-like pathology by CEF along with its
Maria A. Tikhonova, Tamara G. Amstislavskaya, Tamara G. Amstislavskaya, Ying-Jui Ho, Anna A. Akopyan, Michael V. Tenditnik, Marina V. Ovsyukova, Alim A. Bashirzade, Alim A. Bashirzade, Nina I. Dubrovina, Lyubomir I. Aftanas, Lyubomir I. Aftanas   +11 more
doaj   +1 more source

Identification and validation of viral antigens sharing sequence and structural homology with tumor-associated antigens (TAAs).

Journal for ImmunoTherapy of Cancer, 2021
Background The host’s immune system develops in equilibrium with both cellular self-antigens and non-self-antigens derived from microorganisms which enter the body during lifetime. In addition, during the years, a tumor may arise presenting to the immune
Luigi Buonaguro, Maria Lina Tornesello, Franco M Buonaguro, Concetta Ragone, Carmen Manolio, Beatrice Cavalluzzo, Angela Mauriello, Filippo Castiglione, Luigi Vitagliano, Emanuela Iaccarino, Menotti Ruvo, Maria Tagliamonte   +11 more
doaj   +1 more source

Experimental Models of Pancreatitis

Clinical Endoscopy, 2014
Acute pancreatitis is an inflammatory disease characterized by interstitial edema, inflammatory cell infiltration, and acinar cell necrosis, depending on its severity. Regardless of the extent of tissue injury, acute pancreatitis is a completely reversible process with evident normal tissue architecture after recovery. Its pathogenic mechanism has been
Hyun, Jong Jin, Lee, Hong Sik
openaire   +2 more sources

GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration

Neural Plasticity, 2019
In neurons, Glycogen Synthase Kinase-3β (GSK-3β) has been shown to regulate various critical processes underlying structural and functional synaptic plasticity.
Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec   +2 more
doaj   +1 more source

Immunization with a fusion protein vaccine candidate generated from truncated peptides of human enterovirus 71 protects mice from lethal enterovirus 71 infections

Virology Journal, 2020
Background Prophylactic vaccines are critical in preventing hand, foot, and mouth disease (HFMD) primarily caused by human enterovirus 71 (EV71) infection. Children aged less than 5 years are especially susceptible to EV71 infections.
Jiangning Liu, Binbin Zhao, Ling Xue, Jing Wu, Yanfeng Xu, Yongdong Liu, Chuan Qin   +6 more
doaj   +1 more source

Activation of the renal GLP‐1R leads to expression of Ren1 in the renal vascular tree

Endocrinology, Diabetes & Metabolism, 2021
The GLP‐1 receptor (GLP‐1R) in the kidney is expressed exclusively in vascular smooth muscle cells in arteries and arterioles. Downstream effects of the activation of the renal vascular GLP‐1R are elusive but may involve regulation of the renin ...
Katrine Dahl Bjørnholm, Maria Elm Ougaard, Gry Freja Skovsted, Lotte Bjerre Knudsen, Charles Pyke   +4 more
doaj   +1 more source

Experimental models of epilepsy

Medicinski pregled, 2004
Introduction An epileptic seizure is a clinical event and epilepsy is rather a group of symptoms than a disease. The main features all epilepsies have in common include: spontaneous occurrence, repetitiveness, and ictal correlation within the EEG. Epilepsies are manifested with distinct EEG changes, requiring exact clinical definition and consequential
Olivera P, Stanojlović, Dragana P, Zivanović   +1 more
openaire   +3 more sources

Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

Antioxidants, 2018
Vitamin C (vitC) is important in the developing brain, acting both as an essential antioxidant and as co-factor in the synthesis and metabolism of monoaminergic neurotransmitters.
Stine Normann Hansen, Anne Marie V. Schou-Pedersen, Jens Lykkesfeldt, Pernille Tveden-Nyborg   +3 more
doaj   +1 more source

Experimental models for nephropathy [PDF]

Journal of the Renin-Angiotensin-Aldosterone System, 2008
Nephropathy is a leading cause of morbidity and mortality and its prevalence is continuously increasing in industrialised nations. Nephropathy is characterised to varying degrees by nodular glomerulosclerosis, glomerular basement membrane thickness and mesangial expansion, leading to a decline in glomerular filtration rate, persistent elevated ...
Pitchal, Balakumar, Vishal Arvind, Chakkarwar, Vijay, Kumar, Akash, Jain, Jayarami, Reddy, Manjeet, Singh   +5 more
openaire   +2 more sources