Results 51 to 60 of about 114,907,480 (246)

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Role of arachidonic acid cascade in Rhinella arenarum oocyte maturation [PDF]

open access: yes, 2015
There are no studies that document the production of prostaglandins (PGs) or their role in Rhinella arenarum oocyte maturation. In this study, we analysed the effect of arachidonic acid (AA) andprostaglandins (PGs) on maturation, activation and ...
Arias Torres, Ana Josefina   +2 more
core   +1 more source

Evaluation of different factors affecting the efficiency of oocytes cryopreservation in the bovine model [PDF]

open access: yes, 2011
Interest in oocyte cryopreservation has recently increased. Cattle oocytes are sensitive to low temperatures, and despite the efforts of numerous research groups cryopreservation of oocytes remains a difficult task.
De Blasi, Marina
core   +1 more source

In vitro maturation (IVM) of human immature oocytes: is it still relevant?

open access: yesReproductive Biology and Endocrinology, 2023
In vitro maturation (IVM) of human immature oocytes has been shown to be a viable option for patients at risk of ovarian hyperstimulation syndrome (OHSS), those seeking urgent fertility preservation and in circumstances where controlled ovarian ...
Mausumi Das, Weon-Young Son
doaj   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

open access: yesAdvanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen   +11 more
wiley   +1 more source

In vitro maturation of canine oocyte [PDF]

open access: yes, 2005
Compared to other mammals, the canine oocyte offers a very unusual model of meiosis. Its maturation in vitro, studied only over the past ten years, is still poorly controlled: low rate of metaphase II (10 to 20% vs. over 90% in cattle),
REYNAUD, Karine   +9 more
core   +1 more source

Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte [PDF]

open access: yes, 2021
In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART) deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte maturation and in fertility preservation for women facing the risk of ...
Eren, Sibel   +21 more
core   +1 more source

Cytokine-Supplemented Maturation Medium Enhances Cytoplasmic and Nuclear Maturation in Bovine Oocytes

open access: yesAnimals
Bovine in vitro oocyte maturation (IVM) is an easy way to obtain oocytes for subsequent assisted reproductive techniques but is inefficient compared to in vivo maturation.
Renata Blocher   +3 more
doaj   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

open access: yesAnimal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad   +7 more
wiley   +1 more source

Determination of non-invasive viability markers for human embryos in in vitro fertilization. [PDF]

open access: yes, 2010
The major challenge currently facing human in vitro fertilization (IVF) programs is the prevention of multiple gestation pregnancies. The replacement of multiple embryos to fertility patients is common practice to increase pregnancy rates.
Feil, Deanne Kate
core  

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