Results 51 to 60 of about 114,907,480 (246)
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Role of arachidonic acid cascade in Rhinella arenarum oocyte maturation [PDF]
There are no studies that document the production of prostaglandins (PGs) or their role in Rhinella arenarum oocyte maturation. In this study, we analysed the effect of arachidonic acid (AA) andprostaglandins (PGs) on maturation, activation and ...
Arias Torres, Ana Josefina +2 more
core +1 more source
Evaluation of different factors affecting the efficiency of oocytes cryopreservation in the bovine model [PDF]
Interest in oocyte cryopreservation has recently increased. Cattle oocytes are sensitive to low temperatures, and despite the efforts of numerous research groups cryopreservation of oocytes remains a difficult task.
De Blasi, Marina
core +1 more source
In vitro maturation (IVM) of human immature oocytes: is it still relevant?
In vitro maturation (IVM) of human immature oocytes has been shown to be a viable option for patients at risk of ovarian hyperstimulation syndrome (OHSS), those seeking urgent fertility preservation and in circumstances where controlled ovarian ...
Mausumi Das, Weon-Young Son
doaj +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
In vitro maturation of canine oocyte [PDF]
Compared to other mammals, the canine oocyte offers a very unusual model of meiosis. Its maturation in vitro, studied only over the past ten years, is still poorly controlled: low rate of metaphase II (10 to 20% vs. over 90% in cattle),
REYNAUD, Karine +9 more
core +1 more source
Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte [PDF]
In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART) deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte maturation and in fertility preservation for women facing the risk of ...
Eren, Sibel +21 more
core +1 more source
Bovine in vitro oocyte maturation (IVM) is an easy way to obtain oocytes for subsequent assisted reproductive techniques but is inefficient compared to in vivo maturation.
Renata Blocher +3 more
doaj +1 more source
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source
Determination of non-invasive viability markers for human embryos in in vitro fertilization. [PDF]
The major challenge currently facing human in vitro fertilization (IVF) programs is the prevention of multiple gestation pregnancies. The replacement of multiple embryos to fertility patients is common practice to increase pregnancy rates.
Feil, Deanne Kate
core

