Results 1 to 10 of about 2,670,044 (299)

Parkinson’s disease multimodal imaging: F-DOPA PET, neuromelanin-sensitive and quantitative iron-sensitive MRI

npj Parkinson's Disease, 2021
Parkinson’s disease (PD) is a neurodegenerative synucleinopathy characterized by the degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of iron in the substantia nigra (SN).
Frédérique Depierreux, Eric Parmentier, Laurane Mackels, Katherine Baquero, Christian Degueldre, Evelyne Balteau, Eric Salmon, Christophe Phillips, Mohamed Ali Bahri, Pierre Maquet, Gaëtan Garraux   +10 more
doaj   +1 more source

Toetsing in vivo bij ‘In VIVO’ [PDF]

Tijdschrift voor Medisch Onderwijs, 2008
Inleiding: Het In VIVO-project bestaat twee jaar en de implementatie van de nieuwe opleidingsplannen is in volle gang. In dit artikel is de focus gericht op de implementatie van het toets-systeem. Meer specifiek wordt ingegaan op belemmerende en bevorderende factoren met betrekking tot de implementatie van toetsinstrumenten en de percepties van artsen ...
van Luijk, S.J., Scheele, F., van der Vleuten, C.P.M.   +2 more
openaire   +3 more sources

Using quantitative magnetic resonance imaging to track cerebral alterations in multiple sclerosis brain: A longitudinal study

Brain and Behavior, 2023
Introduction Quantitative MRI quantifies tissue microstructural properties and supports the characterization of cerebral tissue damages. With an MPM protocol, 4 parameter maps are constructed: MTsat, PD, R1 and R2*, reflecting tissue physical properties ...
Nora Vandeleene, Camille Guillemin, Solène Dauby, Florence Requier, Maëlle Charonitis, Daphne Chylinski, Evelyne Balteau, Pierre Maquet, Emilie Lommers, Christophe Phillips   +9 more
doaj   +1 more source

Light modulates task-dependent thalamo-cortical connectivity during an auditory attentional task

Communications Biology, 2023
Exposure to blue wavelength light stimulates alertness and performance by modulating a widespread set of task-dependent cortical and subcortical areas.
Ilenia Paparella, Islay Campbell, Roya Sharifpour, Elise Beckers, Alexandre Berger, Jose Fermin Balda Aizpurua, Ekaterina Koshmanova, Nasrin Mortazavi, Puneet Talwar, Christian Degueldre, Laurent Lamalle, Siya Sherif, Christophe Phillips, Pierre Maquet, Gilles Vandewalle   +14 more
doaj   +1 more source

Author Correction: Preserved wake-dependent cortical excitability dynamics predict cognitive fitness beyond age-related brain alterations

Communications Biology, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01995 ...
Maxime Van Egroo, Justinas Narbutas, Daphne Chylinski, Pamela Villar González, Pouya Ghaemmaghami, Vincenzo Muto, Christina Schmidt, Giulia Gaggioni, Gabriel Besson, Xavier Pépin, Elif Tezel, Davide Marzoli, Caroline Le Goff, Etienne Cavalier, André Luxen, Eric Salmon, Pierre Maquet, Mohamed Ali Bahri, Christophe Phillips, Christine Bastin, Fabienne Collette, Gilles Vandewalle   +21 more
doaj   +1 more source

In vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men

Scientific Reports, 2023
The regional integrity of brain subcortical structures has been implicated in sleep–wake regulation, however, their associations with sleep parameters remain largely unexplored.
Puneet Talwar, Michele Deantoni, Maxime Van Egroo, Vincenzo Muto, Daphne Chylinski, Ekaterina Koshmanova, Mathieu Jaspar, Christelle Meyer, Christian Degueldre, Christian Berthomier, André Luxen, Eric Salmon, Fabienne Collette, D.-J. Dijk, Christina Schmidt, Christophe Phillips, Pierre Maquet, Siya Sherif, Gilles Vandewalle   +18 more
doaj   +1 more source

CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria

Scientific Reports, 2021
Phenylketonuria (PKU) is an autosomal recessive inborn error of l-phenylalanine (Phe) metabolism. It is caused by a partial or complete deficiency of the enzyme phenylalanine hydroxylase (PAH), which is necessary for conversion of Phe to tyrosine (Tyr ...
Kuldeep Singh, Cathleen S. Cornell, Robert Jackson, Mostafa Kabiri, Michael Phipps, Mitul Desai, Robert Fogle, Xiaoyou Ying, Gulbenk Anarat-Cappillino, Sarah Geller, Jennifer Johnson, Errin Roberts, Katie Malley, Tim Devlin, Matthew DeRiso, Patricia Berthelette, Yao V. Zhang, Susan Ryan, Srinivas Rao, Beth L. Thurberg, Dinesh S. Bangari, Sirkka Kyostio-Moore   +21 more
doaj   +1 more source

Fully automated 18F-fluorination of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) for indirect labelling of nanobodies

Scientific Reports, 2022
N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB), a widely used labeling agent to introduce the 4-[18F]fluorobenzoyl-prosthetic group, is normally obtained in three consecutive steps from [18F]fluoride ion. Here, we describe an efficient one-step labeling
Surasa Nagachinta, Paolo Novelli, Yoann Joyard, Nicolas Maindron, Patrick Riss, Sylvestre Dammicco   +5 more
doaj   +1 more source

Brain correlates of perceived cognitive impairment after covid-19 infection: a multimodal MRI study.

European Psychiatry, 2023
Introduction Many different long-term neuropsychiatric sequelae of the novel Coronavirus have been described after the pandemic outbreak. One of the most common symptoms in the months following infection is related to “brain fog”.
V. Bettonagli, M. Paolini, M. Palladini, M. G. Mazza, P. Rovere Guerini, S. Poletti, F. Benedetti   +6 more
doaj   +1 more source

Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice

Reproductive Medicine and Biology, 2022
Background The protein proAKAP4 is crucial for sperm motility and has been suggested as an indicator of male fertility. We determined the relationship between proAKAP4 concentration and sperm motility parameters in mice, and investigated the effects of ...
Auke Boersma, Jasmin Primus, Bettina Wagner, Veronika Broukal, Lill Andersen, Barbara Pachner, Maik Dahlhoff, Thomas Rülicke, Kerstin E. Auer   +8 more
doaj   +1 more source