Results 11 to 20 of about 2,670,044 (299)
Clocks & Sleep, 2023 Light use is rising steeply, mainly because of the advent of light-emitting diode (LED) devices. LEDs are frequently blue-enriched light sources and may have different impacts on the non-image forming (NIF) system, which is maximally sensitive to blue ...
Islay Campbell +2 more
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The impact of percutaneous epididymal sperm aspiration on sperm quality in mice
Reproduction and Fertility, 2023 In laboratory mice, sperm quality is usually assessed in spermatozoa collected from the cauda epididymidis of freshly sacrificed males. Percutaneous epididymal sperm aspiration (PESA) is a non-terminal alternative that would allow repeated sperm ...
Lisa Windhofer +4 more
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Molecular Therapy: Oncolytics, 2016 We have engineered an integration-deficient lentiviral vector, LV305, to deliver the tumor antigen NY-ESO-1 to human dendritic cells in vivo through pseudotyping with a modified Sindbis virus envelop protein.
Tina Chang Albershardt +5 more
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Frontiers in Pharmacology, 2020 AimsTo describe the effects of the KCa2 channel inhibitor AP30663 in pigs regarding tolerability, cardiac electrophysiology, pharmacokinetics, atrial functional selectivity, effectiveness in cardioversion of tachy-pacing induced vernakalant-resistant ...
Jonas Goldin Diness +10 more
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Dermatology Research and Practice, 2010 The structure, function, and regulation of desmosomal adhesion in vivo are discussed. Most desmosomes in tissues exhibit calcium‐independent adhesion, which is strongly adhesive or “hyperadhesive”. This is fundamental to tissue strength. Almost all studies in culture are done on weakly adhesive, calcium‐dependent desmosomes, although hyperadhesion can ...
openaire +4 more sources
Frontiers in Psychiatry, 2021 While anosognosia is often present in Alzheimer's disease, the degree of awareness of cognitive difficulties in the earlier stages, such as Mild Cognitive Impairment (MCI), is less clear.
Christine Bastin +7 more
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eLife, 2022 Sleep alteration is a hallmark of ageing and emerges as a risk factor for Alzheimer’s disease (AD). While the fine-tuned coalescence of sleep microstructure elements may influence age-related cognitive trajectories, its association with AD processes is ...
Daphne Chylinski +13 more
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Trends in Microbiology, 2013 Bacteria can grow and proliferate either as single, independent cells or organized in aggregates commonly referred to as biofilms. When bacteria succeed in forming a biofilm within the human host, the infection often becomes very resistant to treatment and can develop into a chronic state.
Morten Alhede +12 more
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Molecules, 2021 Alterations in viscosity of biological fluids and tissues play an important role in health and diseases. It has been demonstrated that the electron paramagnetic resonance (EPR) spectrum of a 13C-labeled trityl spin probe (13C-dFT) is highly sensitive to ...
Murugesan Velayutham +4 more
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Dopamine Neuron Challenge Test for early detection of Parkinson’s disease
npj Parkinson's Disease, 2021 Diagnosing Parkinson’s disease (PD) before the clinical onset proves difficult because the hallmark PD symptoms do not manifest until more than 60% of dopamine neurons in the substantia nigra pars compacta have been lost.
Jingheng Zhou +4 more
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