Results 31 to 40 of about 2,670,044 (299)

Aortic Slimgraft: Ex vivo and in vivo study [PDF]

Journal of Vascular Surgery, 2001
In this article we describe a method for assembling an endovascular graft within the aorta with a graft and then a stent introduced sequentially over a guidewire as separate components. In the ex vivo study, an endovascular graft that was 25 mm in diameter was introduced through a 9F introducer.
Julio I. Osende, John T. Fallon, Juan J. Badimon, Andrew S. Kerr   +3 more
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Endocannabinoid signaling is critical for habit formation

Frontiers in Integrative Neuroscience, 2007
Extended training can induce a shift in behavioral control from goal-directed actions, which are governed by action-outcome contingencies and sensitive to change in the expected value of the outcome, to habits which are less dependent on action-outcome ...
Monica R. F Hilário, Emily Clouse, Henry H Yin, Rui M Costa   +3 more
doaj   +1 more source

Mate genetic similarity affects mating behaviour but not maternal investment in mice

Scientific Reports, 2023
Maternal investment can affect the survival and development of offspring. Here we experimentally investigated in mice, whether females alter implantation rates and pup survival after embryo transfer depending on the genetic similarity with their ...
Kerstin E. Auer, Jasmin Primus, Sonja Istel, Maik Dahlhoff, Thomas Rülicke   +4 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Association between sleep slow-wave activity and in-vivo estimates of myelin in healthy young men

NeuroImage, 2023
Sleep has been suggested to contribute to myelinogenesis and associated structural changes in the brain. As a principal hallmark of sleep, slow-wave activity (SWA) is homeostatically regulated but also differs between individuals. Besides its homeostatic
Michele Deantoni, Marion Baillet, Gregory Hammad, Christian Berthomier, Mathilde Reyt, Mathieu Jaspar, Christelle Meyer, Maxime Van Egroo, Puneet Talwar, Eric Lambot, Sarah L. Chellappa, Christian Degueldre, André Luxen, Eric Salmon, Evelyne Balteau, Christophe Phillips, Derk-Jan Dijk, Gilles Vandewalle, Fabienne Collette, Pierre Maquet, Vincenzo Muto, Christina Schmidt   +21 more
doaj  

Beyond the Barrier: Targeted Radionuclide Therapy in Brain Tumors and Metastases

Pharmaceutics, 2019
Brain tumors are notoriously difficult to treat. The blood-brain barrier provides a sanctuary site where residual and metastatic cancer cells can evade most therapeutic modalities.
Janik Puttemans, Tony Lahoutte, Matthias D’Huyvetter, Nick Devoogdt   +3 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Circadian regulation of human cortical excitability

Nature Communications, 2016
Cognitive performance is impaired after prolonged wakefulness, yet the contribution of circadian rhythms for proper brain function remains unclear. Here the authors show that cortical excitability measured using TMS exhibits robust circadian dynamics ...
Julien Q. M. Ly, Giulia Gaggioni, Sarah L. Chellappa, Soterios Papachilleos, Alexandre Brzozowski, Chloé Borsu, Mario Rosanova, Simone Sarasso, Benita Middleton, André Luxen, Simon N. Archer, Christophe Phillips, Derk-Jan Dijk, Pierre Maquet, Marcello Massimini, Gilles Vandewalle   +15 more
doaj   +1 more source

The Canmore Declaration: Statement of Principles for Planetary Health

Challenges, 2018
The term planetary health—denoting the interdependence between human health and place at all scales—emerged from the environmental and preventive health movements of the 1970–80s; in 1980, Friends of the Earth expanded the World Health Organization ...
Susan L. Prescott, Alan C. Logan, Glenn Albrecht, Dianne E. Campbell, Julian Crane, Ashlee Cunsolo, John W. Holloway, Anita L. Kozyrskyj, Christopher A. Lowry, John Penders, Nicole Redvers, Harald Renz, Jakob Stokholm, Cecilie Svanes, Ganesa Wegienka, on Behalf of inVIVO Planetary Health, of the Worldwide Universities Network (WUN)   +15 more
doaj   +1 more source