Results 51 to 60 of about 7,607,147 (352)

Ultrasound imaging for assessing aortic phenotypes: A preclinical tool for measuring cardiac disease model progression and therapeutic effect

WFUMB Ultrasound Open
Cardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1).
James Cao, Alex Jayyosi, Jennifer Nietupski, Giulio Tomassy, Ingeborg M. Langohr, Michelle Potter, Srinivas Rao, Dinesh S. Bangari, Xiaoyou Ying   +8 more
doaj   +1 more source

Endocannabinoid signaling is critical for habit formation

Frontiers in Integrative Neuroscience, 2007
Extended training can induce a shift in behavioral control from goal-directed actions, which are governed by action-outcome contingencies and sensitive to change in the expected value of the outcome, to habits which are less dependent on action-outcome ...
Monica R. F Hilário, Emily Clouse, Henry H Yin, Rui M Costa   +3 more
doaj   +1 more source

Aktivitas Antiplasmodium in Vivo Fraksi N-butanol Kulit Batang Mahoni (Swietenia Mahagoni) Dan Asam Klorogenat [PDF]

, 2011
An antiplasmodial activity of n-butanol fraction from mahoni bark extract (Swietenia mahagoni Jacq.) and pure compound chlorogenic acid were investigated on white male miceSwiss derivated strain which were infected by Plasmodium berghei ANKA strain ...
Lukmayani, Y. (Yani), Muis, A. (Abdul), S, G. P. (Glorida), Supriyatna, S. (Supriyatna)   +3 more
core  

In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]

, 2009
Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Brand, Braun, Carton, Evans, Evans, Goto, Hartenstein, Hoffmann, Hultmark, Konrad, Kurucz, Kurucz, Kurucz, Lanot, Metaxakis, Márkus, Márkus, Zettervall   +17 more
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Circadian regulation of human cortical excitability

Nature Communications, 2016
Cognitive performance is impaired after prolonged wakefulness, yet the contribution of circadian rhythms for proper brain function remains unclear. Here the authors show that cortical excitability measured using TMS exhibits robust circadian dynamics ...
Julien Q. M. Ly, Giulia Gaggioni, Sarah L. Chellappa, Soterios Papachilleos, Alexandre Brzozowski, Chloé Borsu, Mario Rosanova, Simone Sarasso, Benita Middleton, André Luxen, Simon N. Archer, Christophe Phillips, Derk-Jan Dijk, Pierre Maquet, Marcello Massimini, Gilles Vandewalle   +15 more
doaj   +1 more source

The Canmore Declaration: Statement of Principles for Planetary Health

Challenges, 2018
The term planetary health—denoting the interdependence between human health and place at all scales—emerged from the environmental and preventive health movements of the 1970–80s; in 1980, Friends of the Earth expanded the World Health Organization ...
Susan L. Prescott, Alan C. Logan, Glenn Albrecht, Dianne E. Campbell, Julian Crane, Ashlee Cunsolo, John W. Holloway, Anita L. Kozyrskyj, Christopher A. Lowry, John Penders, Nicole Redvers, Harald Renz, Jakob Stokholm, Cecilie Svanes, Ganesa Wegienka, on Behalf of inVIVO Planetary Health, of the Worldwide Universities Network (WUN)   +15 more
doaj   +1 more source

Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage [PDF]

, 2006
Novel substituted 2-methyl-3-indolylacetic derivatives were synthesized and evaluated for their activity in vitro and in vivo on COX-1 and COX-2. Active compounds were screened to determine their gastrointestinal tolerability in vivo in the rat.
C. Renner, CALIENDO, GIUSEPPE, CIRINO, GIUSEPPE, FIORINO, FERDINANDO, PERISSUTTI, ELISA, ROSSI, ANTONIETTA, ROVIEZZO, FIORENTINA, SANTAGADA, VINCENZO, SAUTEBIN, LIDIA, SEVERINO, BEATRICE   +9 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Uji Aktivitas Antidislipidemia In Vivo Fraksi Ekstrak Daun Salam (Eugenia Polyantha) pada Tikus Galur Wistar yang Diinduksi Diet Tinggi Lemak [PDF]

, 2014
Dislipidemia merupakan faktor resiko berbagai penyakit yang masih menjadi masalah besar di Indonesia. Daun salam (Eugenia polyantha) terbukti dapat digunakan sebagai antidislipidemia.Untuk mengetahui fraksi apakah yang berpengaruh terhadap aktivitas ...
Chalista, S. (Shelvia), Fam, F. I. (Felicia), Irmadoly, N. (Nini), Se, H. S. (Ha), Wirajaya, F. (Frandy)   +4 more
core