Results 51 to 60 of about 2,670,044 (299)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Homeostatic sleep regulation in the absence of the circadian sleep‐regulating component: effect of short light–dark cycles on sleep–wake stages and slow waves

BMC Neuroscience, 2021
Background Aside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation. Light exerts indirect sleep effect by modulating the circadian rhythms. Exposure to short light-dark cycle
Örs Szalontai, Attila Tóth, Máté Pethő, Dóra Keserű, Tünde Hajnik, László Détári   +5 more
doaj   +1 more source

Diana, in vivo

Cuadernos de Información y Comunicación, 2004
A partir de un análisis del drama provocado durante algunas semanas en la sociedad británica por la muerte accidental de la Princesa Diana en 1997, este artículo propone una interpretación de los sutiles cambios que afectan hoy día a las relaciones comunicativas en el campo político.
openaire   +4 more sources

Ex vivo and in vivo coronary ostial locations in humans [PDF]

Surgical and Radiologic Anatomy, 2009
Surgical and radiologic anatomy, 31 (8)
Knight, J, Kurtcuoglu, V, Muffly, K, Marshall Jr, W, Stolzmann, P, Desbiolles, L, Seifert, B, Poulikakos, D, Alkadhi, H   +8 more
openaire   +5 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Genetic risk for insomnia is associated with objective sleep measures in young and healthy good sleepers

Neurobiology of Disease, 2022
Insomnia disorder (ID) is the second most common neuropsychiatric disorder. Its socioeconomic burden is enormous while diagnosis and treatment are difficult.
Ekaterina Koshmanova, Vincenzo Muto, Daphne Chylinski, Charlotte Mouraux, Mathilde Reyt, Martin Grinard, Puneet Talwar, Erik Lambot, Christian Berthomier, Marie Brandewinder, Nasrin Mortazavi, Christian Degueldre, André Luxen, Eric Salmon, Michel Georges, Fabienne Collette, Pierre Maquet, Eus Van Someren, Gilles Vandewalle   +18 more
doaj  

The Rise of Synaptic Density PET Imaging

Molecules, 2020
Many neurological disorders are related to synaptic loss or pathologies. Before the boom of positrons emission tomography (PET) imaging of synapses, synaptic quantification could only be achieved in vitro on brain samples after autopsy or surgical ...
Guillaume Becker, Sylvestre Dammicco, Mohamed Ali Bahri, Eric Salmon   +3 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Individual in vivo Profiles of Microglia Polarization After Stroke, Represented by the Genes iNOS and Ym1

Frontiers in Immunology, 2019
Microglia are the brain-innate immune cells which actively surveil their environment and mediate multiple aspects of neuroinflammation, due to their ability to acquire diverse activation states and phenotypes. Simplified, M1-like microglia are defined as
Franziska M. Collmann, Rory Pijnenburg, Somayyeh Hamzei-Taj, Anuka Minassian, Kat Folz-Donahue, Christian Kukat, Markus Aswendt, Markus Aswendt, Mathias Hoehn, Mathias Hoehn, Mathias Hoehn   +10 more
doaj   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source