ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
From Sea to Cell: <i>Ascophyllum nodosum</i> and <i>Fucus vesiculosus</i> Extracts Attenuate NF-κB-Mediated Inflammation and Protect Intestinal Barrier Integrity-A Comprehensive Analysis Applying In Vitro and In Vivo Models. [PDF]
Karlsberger L +10 more
europepmc +1 more source
<i>In vivo</i> models to study gastrointestinal <i>Salmonella</i> infections. [PDF]
Thiers I, Lories B, Steenackers H.
europepmc +1 more source
Single-cell and bulk transcriptomics reveal Fusobacterium nucleatum promotes colorectal cancer metastasis by upregulating LAMC2 in in vitro and in vivo models. [PDF]
Ran S +8 more
europepmc +1 more source
Evaluation of Drug Permeation Enhancement by Using In Vitro and Ex Vivo Models. [PDF]
Steyn JD +6 more
europepmc +1 more source
TRPV1 Blocker, Peptide HCRG21 from Sea Anemone <i>Heteractis magnifica</i>, Exhibits Effectiveness in Psoriasis and Dermatitis in In Vivo Models. [PDF]
Klimovich A +9 more
europepmc +1 more source
Characterization and Pathogenicity of Equine Herpesvirus Type 8 Using In-Vitro and In-Vivo Models. [PDF]
Ji Y +6 more
europepmc +1 more source

