Results 121 to 130 of about 433 (162)

Regulation of X-chromosome inactivation by the X-inactivation centre

Nature Reviews Genetics, 2011
X-chromosome inactivation (XCI) ensures dosage compensation in mammals and is a paradigm for allele-specific gene expression on a chromosome-wide scale. Important insights have been made into the developmental dynamics of this process. Recent studies have identified several cis- and trans-acting factors that regulate the initiation of XCI via the X ...
Sandrine Augui, Elphège P. Nora, Edith Heard   +2 more
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INACTIVATION OF PICORNAVIRUSES AND CALICIVIRUSES; Part 2: Inactivation

The Thai Journal of Veterinary Medicine, 2003
The prevention of human fecal contamination of food and water is an effective measure to control the transmission of foodborne disease viruses e.g. hepatitis A virus (HAV) and calicivirus found in food chains and water systems. If the prevention of virus contamination is not successful, one of the most common critical control points in the food ...
Suphachai Nuanualsuwan, Dean O. Cliver
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Evaluation of Disinfectant Inactivators

Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology, 1972
A procedure for the control of disinfectant inactivators is described and suitable antagonists for some disinfectants are listed.
T, Bergan, A, Lystad
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Ribosome-inactivating proteins

Toxicon, 1997
Abstract Ribosome-inactivating proteins (RIPs, review by Barbieri et a/. 1993) are a class of proteins present in various tissues of several plants which inactivate mammalian ribosomes and, with less activity and to variable extent, plant, fungal, and bacterial ribosomes. They are enzymes, N-glycosidases, which release adenine from rRNA.
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X inactivation Xplained

Current Opinion in Genetics & Development, 2007
Random inactivation of one of the two female X chromosomes establishes dosage compensation between XY males and XX females in placental mammals. X inactivation is controlled by the X inactivation center (Xic). Recent advances in genome sequencing show that the Xic has evolved from an ancestral vertebrate gene cluster in placental mammals and has ...
Wutz, A, Gribnau, Joost
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Photodynamic inactivation of poliovirus

Virology, 1963
Abstract Poliovirus, as usually found in fluids of infected cultures, cannot be inactivated photodynamically in the presence of heterotricyclic dyes. However, if the mature virus is freed of extraneous organic material, dyes can attach to the virus and render it light-sensitive.
C, WALLIS, J L, MELNICK
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An Inactivated

JAMA, 1965
An experimental vaccine was prepared withMycoplasma pneumonia, the agent of primary atypical pneumonia. Its injection elicited antibody in rabbits and monkeys and induced resistance to multiplication of myoplasma in lungs of vaccinated hamsters. The vaccine was well tolerated in preliminary studies with 36 human subjects, and encouraging evidence of ...
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Inactivation of the X-Chromosome

New England Journal of Medicine, 1972
IN its classic form, the hypothesis of X-chromosome inactivation holds that only one of the two X-chromosomes present in cells of female mammals is functional. The "decision" of which X-chromosome is to operate in a cell occurs quite early in embryogenesis and, once made, is irreversible for that cell and all its progeny.
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Biogenesis and Inactivation of Catecholestrogens

1997
Publisher Summary Catecholestrogens (CEs) can be generated by several discrete enzymatic pathways that can result in the formation of both 2- and 4- hydroxylated CEs (4-OH-CEs). These two classes of CEs differ in their properties both as catechols and as estrogens (Es). This chapter summarizes the value of these insights, availability of specific and
J, Weisz, G A, Clawson, C R, Creveling
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Enzymatic Inactivation of Secretin

Nature, 1951
THE inactivation of secretin by whole blood, cell-free plasma, serum and urine has been demonstrated by Greengard and Ivy1,2 to be an enzymatic process. Because of the stability of their secretin preparations towards crystalline pepsin and trypsin and the absence of detectable proteolytic activity of blood, they concluded that ‘secretinase’ was not a ...
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