Results 131 to 140 of about 367 (165)
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Journal of Virological Methods, 2017
Rabies virus is a notifiable pathogen that must be handled in high containment facilities where national and international guidelines apply. For the effective inactivation of rabies virus, a number of reagents were tested. Virkon S (1%) solution caused more than 4log reduction of rabies virus in culture medium supplemented with 10% foetal calf serum ...
Guanghui, Wu +3 more
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Rabies virus is a notifiable pathogen that must be handled in high containment facilities where national and international guidelines apply. For the effective inactivation of rabies virus, a number of reagents were tested. Virkon S (1%) solution caused more than 4log reduction of rabies virus in culture medium supplemented with 10% foetal calf serum ...
Guanghui, Wu +3 more
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Photodynamic inactivation of poliovirus
Virology, 1963Abstract Poliovirus, as usually found in fluids of infected cultures, cannot be inactivated photodynamically in the presence of heterotricyclic dyes. However, if the mature virus is freed of extraneous organic material, dyes can attach to the virus and render it light-sensitive.
C, WALLIS, J L, MELNICK
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JAMA, 1965
An experimental vaccine was prepared withMycoplasma pneumonia, the agent of primary atypical pneumonia. Its injection elicited antibody in rabbits and monkeys and induced resistance to multiplication of myoplasma in lungs of vaccinated hamsters. The vaccine was well tolerated in preliminary studies with 36 human subjects, and encouraging evidence of ...
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An experimental vaccine was prepared withMycoplasma pneumonia, the agent of primary atypical pneumonia. Its injection elicited antibody in rabbits and monkeys and induced resistance to multiplication of myoplasma in lungs of vaccinated hamsters. The vaccine was well tolerated in preliminary studies with 36 human subjects, and encouraging evidence of ...
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Polyomavirus inactivation – A review
Biologicals, 2013Polyomavirus inactivation has been studied since the 1950s when it became apparent that certain polio vaccines were contaminated with SV40. Relatively high temperatures (≥70 °C) are required to effect thermal inactivation of the polyomaviruses. The chemical inactivants that are effective (β-propiolactone, ethanol, sodium hydroxide, and formaldehyde ...
Raymond W, Nims, Mark, Plavsic
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Inactivation of the X-Chromosome
New England Journal of Medicine, 1972IN its classic form, the hypothesis of X-chromosome inactivation holds that only one of the two X-chromosomes present in cells of female mammals is functional. The "decision" of which X-chromosome is to operate in a cell occurs quite early in embryogenesis and, once made, is irreversible for that cell and all its progeny.
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Enzymatic Inactivation of Secretin
Nature, 1951THE inactivation of secretin by whole blood, cell-free plasma, serum and urine has been demonstrated by Greengard and Ivy1,2 to be an enzymatic process. Because of the stability of their secretin preparations towards crystalline pepsin and trypsin and the absence of detectable proteolytic activity of blood, they concluded that ‘secretinase’ was not a ...
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Biogenesis and Inactivation of Catecholestrogens
1997Publisher Summary Catecholestrogens (CEs) can be generated by several discrete enzymatic pathways that can result in the formation of both 2- and 4- hydroxylated CEs (4-OH-CEs). These two classes of CEs differ in their properties both as catechols and as estrogens (Es). This chapter summarizes the value of these insights, availability of specific and
J, Weisz, G A, Clawson, C R, Creveling
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THE INACTIVATION OF TRYPSIN : III. SPONTANEOUS INACTIVATION.
The Journal of general physiology, 20101. The rate of inactivation of purified trypsin solutions approximates closely that demanded by the monomolecular formula. The more carefully the solution is purified the closer the agreement with the formula. 2. The products formed by the action of trypsin on proteins renders the trypsin more stable. Gelatin and glycine have no effect. 3.
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Cell inactivation by ultrasound
Biotechnology and Bioengineering, 1976AbstractCell survival curves have been obtained for Escherichia coli B (E. coli B) after the sonication of suspensions of the bacteria with continuous wave ultrasound at a fixed frequency of 2 MHz between peak intensities of 8.7 and 2.25 W cm−2. It was found that under suitable conditions the survival curves were reproducible and it also was found that
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