Results 111 to 120 of about 2,682,884 (340)

Diagnosis and treatment of progressive multiple sclerosis: A position paper

European Journal of Neurology, Volume 30, Issue 1, Page 9-21, January 2023., 2023
Abstract Background and Purpose Multiple sclerosis (MS) is an unpredictable disease characterised by a highly variable disease onset and clinical course. Three main clinical phenotypes have been described. However, distinguishing between the two progressive forms of MS can be challenging for clinicians.
Carlo Pozzilli, Maura Pugliatti, Patrick Vermersch, Nikolaos Grigoriadis, Mona Alkhawajah, Laura Airas, Celia Oreja‐Guevara   +6 more
wiley   +1 more source

Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs

The Journal of Clinical Investigation, 2023
Since 2003, rare inborn errors of human type I IFN immunity have been discovered, each underlying a few severe viral illnesses. Autoantibodies neutralizing type I IFNs due to rare inborn errors of autoimmune regulator (AIRE)–driven T cell tolerance were ...
Jean-Laurent Casanova, Mark S. Anderson
doaj   +1 more source

Models of Innate Neural Attractors and Their Applications for Neural Information Processing [PDF]

arXiv, 2015
In this work we reveal and explore a new class of attractor neural networks, based on inborn connections provided by model molecular markers, the molecular marker based attractor neural networks (MMBANN). We have explored conditions for the existence of attractor states, critical relations between their parameters and the spectrum of single neuron ...
arxiv  

Healthcare Quality by Specialists Under a Mixed Compensation System: An Empirical Analysis

Health Economics, EarlyView.
ABSTRACT We analyze the effects of a mixed compensation (MC) scheme for specialists on the quality of their healthcare services. We exploit a reform implemented in Quebec (Canada) in 1999. The government introduced a payment mechanism combining a per diem with a reduced fee per clinical service.
Damien Echevin, Bernard Fortin, Aristide Houndetoungan   +2 more
wiley   +1 more source

The interference immunity of the telemetric information data exchange with autonomous mobile robots [PDF]

Naukovyi Visnyk Natsionalnoho Hirnychoho Universytetu, no. 1, pp. 107-113, 2015, 2015
Purpose. To obtain the interference immunity of the data exchange by spread spectrum signals with variable entropy of the telemetric information data exchange with autonomous mobile robots. Methodology. The results have been obtained by the theoretical investigations and have been confirmed by the modeling experiments. Findings.
arxiv  

Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency

Head &Neck, EarlyView.
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi, James A. Stewart, Kirk Withrow, Carissa M. Thomas   +3 more
wiley   +1 more source

On Carr and Lee's correlation immunization strategy [PDF]

arXiv, 2018
In their seminal work Carr and Lee (2008) show how to robustly price and replicate a variety of claims written on the quadratic variation of a risky asset under the assumption that the asset's volatility process is independent of the Brownian motion that drives the asset's price.
arxiv  

Introgression of a synthetic sex ratio distortion transgene into different genetic backgrounds of Anopheles coluzzii

Insect Molecular Biology, Volume 32, Issue 1, Page 56-68, February 2023., 2023
The introgression of a synthetic sex ratio distortion transgene into two different genetic backgrounds of Anopheles coluzzii by six backcrosses. We showed that the phenotype of the sex ratio distorter is stabile in the introgressed An. coluzzii strains.
Paola Pollegioni, Tania Persampieri, Roxana L. Minuz, Alessandro Bucci, Alessandro Trusso, Salvatore Di Martino, Chiara Leo, Marco Bruttini, Marco Ciolfi, Ann‐Marie Waldvogel, Frédéric Tripet, Alekos Simoni, Andrea Crisanti, Ruth Müller   +13 more
wiley   +1 more source

Break down the barriers of auto‐inflammation: How to deal with a monogenic auto‐inflammatory disease and immuno‐haematological features in 2022?

Immunology, Volume 168, Issue 1, Page 1-17, January 2023., 2023
In the past few years, the spectrum of monogenic systemic auto‐inflammatory diseases has widely expanded beyond the typical recurrent fever. Immuno‐haematological features, as cytopenias, hypogammaglobulinemia, hypereosinophilia, lymphoproliferation and immunodeficiency, have been described in association of several MSAID.
Hélène Vergneault, Capucine Picard, Sophie Georgin‐Lavialle   +2 more
wiley   +1 more source

Red flags to suspect inborn errors of immunity in patients with autoimmune diseases

Biomédica: revista del Instituto Nacional de Salud
Inborn errors of immunity are monogenic disorders that predispose patients to immune dysregulation, autoimmunity, and infection. Some autoimmune diseases, such as autoimmune cytopenias, systemic lupus erythematosus, and inflammatory bowel diseases, are ...
Natalia Vélez, Juliette De Ávila, Jaime Cortés, Nelson Barrero, Leosirlay Rojas, Juan Manuel Bello, Consuelo Romero-Sánchez   +6 more
doaj   +1 more source