Results 141 to 150 of about 2,682,884 (340)

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Breastfeeding duration is associated with higher adiposity at 6–8 months of age

Maternal &Child Nutrition, Volume 19, Issue 1, January 2023., 2023
Our study found that infants who received breastfeeding (BF) solely for a longer duration had significantly higher fat mass and fat mass index at age 6–8 months based on anthropometry and isotope dilution technique compared with infants with a shorter BF duration.
Thanida Ua‐areechit, Orapa Suteerojntrakool, Tippawan Pongcharoen, Pattanee Winichagoon, Kunchit Judprasong, Alexia J. Murphy‐Alford, Warren T. K. Lee, Bubphachat Potip, Pimnapanut Sridonpai, Wanabhorn Tongchom, Sirinuch Chomtho   +10 more
wiley   +1 more source

Targeted NGS Yields Plentiful Ultra-Rare Variants in Inborn Errors of Immunity Patients [PDF]

, 2021
Alice Grossi, Maurizio Miano, Marina Lanciotti, Francesca Fioredda, Daniela Guardo, Elena Palmisani, Paola Terranova, Giuseppe Santamaria, Francesco Caroli, Roberta Caorsi, Stefano Volpi, Marco Gattorno, Carlo Dufour, Isabella Ceccherini   +13 more
openalex   +1 more source

Serious Neurologic Adverse Events in Tofersen Clinical Trials for Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is approved for the treatment of amyotrophic lateral sclerosis (ALS) due to superoxide dismutase 1 mutations (SOD1‐ALS). Here we report serious neurologic adverse events (AEs) that occurred in the tofersen clinical trials in people with SOD1‐ALS.
Alexandra Lovett, Sowmya Chary, Suma Babu, Gaëlle Bruneteau, Jonathan D. Glass, Merete Karlsborg, Shafeeq Ladha, Keith Mayl, Christopher McDermott, Robert C. Bucelli, Adriano Chiò, Toby A. Ferguson, Thos Cochrane, Stephanie Fradette, Karen Smirnakis, Jennifer Inra, Sohail Malek, Laura Fanning   +17 more
wiley   +1 more source

Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee [PDF]

, 2020
Stuart G. Tangye, Waleed Al‐Herz, Aziz Bousfiha, Talal A. Chatila, Charlotte Cunningham‐Rundles, Amos Etzioni, José Luis Franco, Steven M. Holland, Christoph Klein, Tomohiro Morio, Hans D. Ochs, Éric Oksenhendler, Capucine Pïcard, Jennifer M. Puck, Troy R. Torgerson, Jean‐Laurent Casanova, Kathleen E. Sullivan   +16 more
openalex   +1 more source

Towards a Conceptual Framework for Innate Immunity [PDF]

Proceedings of the 4th International Conference on Artificial Immune Systems (ICARIS 2005), Lecture Notes in Computer Science 3627, Banff, Canada, p 112-125, 2010
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity. This paper reviews the biological principles and properties of innate immunity and, adopting a conceptual framework, asks how these can be incorporated into artificial models.
arxiv  

Comparing Comorbidity Indices to Predict Survival After Pediatric Hematopoietic Stem Cell Transplantation for Nonmalignant Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for children with hematological or immunological disorders. However, treatment‐related morbidity and mortality remain concerning. Various comorbidity indices are currently used to assess the risk of complications following pediatric HCT.
Roos Lotte Alexandra Bukman, Anne B. Verbeek, Arjan C. Lankester, Erik G. J. von Asmuth, Emilie Pauline Buddingh   +4 more
wiley   +1 more source

An Overview of the Strategies to Boost SARS-CoV-2-Specific Immunity in People with Inborn Errors of Immunity [PDF]

The SARS-CoV-2 pandemic has heightened concerns about immunological protection, especially for individuals with inborn errors of immunity (IEI). While COVID-19 vaccines elicit strong immune responses in healthy individuals, their effectiveness in IEI ...
Chang-Rabley, Emma, Edwards, Emily S.J., Ricotta, Emily E., van Zelm, Menno C.   +3 more
core   +1 more source

Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity [PDF]

, 2020
Emilia Cirillo, Giuliana Giardino, Silvia Ricci, Viviana Moschese, Vassilios Lougaris, Francesca Conti, Chiara Azzari, Federica Barzaghi, Clementina Canessa, Baldassarre Martire, Raffaele Badolato, Laura Dotta, Annarosa Soresina, Caterina Cancrini, Andrea Finocchi, Davide Montin, Roberta Romano, Donato Amodio, Francesca Ferrua, Alberto Tommasini, Lucia Augusta Baselli, Rosa Maria Dellepiane, Agata Polizzi, Luciana Chessa, Antonio Marzollo, Maria Pia Cicalese, Maria Caterina Putti, Andrea Pession, Alessandro Aiuti, Franco Locatelli, Alessandro Plebani, Claudio Pignata   +31 more
openalex   +1 more source

Epidemic spreading with immunization rate on complex networks [PDF]

arXiv, 2011
We investigate the spread of diseases, computer viruses or information on complex networks and also immunization strategies to prevent or control the spread. When an entire population cannot be immunized and the effect of immunization is not perfect, we need the targeted immunization with immunization rate.
arxiv