Results 181 to 190 of about 7,598 (255)

The Etiologic Landscape of Lymphoproliferation in Childhood: Proposal for a Diagnostic Approach Exploring from Infections to Inborn Errors of Immunity and Metabolic Diseases

Giorgio Costagliola, Emanuela De Marco, Francesco Massei, Giulia Roberti, Fabrizio Catena, Gabriella Casazza, Rita Consolini   +6 more
openalex   +2 more sources

Ancestral Origin and Structural Characteristics of Non‐Syntenic Homologous Chromosomes in Abalones (Haliotis)

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Structural variation is increasingly recognised as a pivotal contributor to genomic diversity in marine invertebrates, yet its extent and evolutionary significance remain poorly characterised in many species. Haplotype‐phased genome assembly is an excellent resource for studying such variations by comparing homologous chromosomes.
Shotaro Hirase, Takashi Makino, Takeshi Takeuchi, Mitsutaka Kadota, Shigehiro Kuraku, Kiyoshi Kikuchi   +5 more
wiley   +1 more source

Pathological IgE Production in Inborn Errors of Immunity and Beyond. [PDF]

Immunol Rev
Ma CS, Hsu PS.
europepmc   +1 more source

"It's a Godsend": Parental experiences of genomic testing for paediatric inborn errors of immunity. [PDF]

Eur J Hum Genet
Clark A, DeBortoli E, Blancoe M, Sgro C, Clinch T, Melo M, Pinzon-Charry A, Sullivan A, McInerney-Leo A, Peake J, McNaughton P, Yanes T.   +11 more
europepmc   +1 more source

Health-related quality of life among a group of Egyptian children with inborn errors of immunity: a cross-sectional study [PDF]

Yehia El-gamal, Azza M. Youssef, A. M. El sayed, Nesrine Radwan   +3 more
openalex   +1 more source

Primary Antibody Deficiency in Patients With Chronic Rhinosinusitis: A Call for Immunologic Evaluation Prior to Biologic Therapy

Clinical Otolaryngology, Volume 51, Issue 1, Page 144-152, January 2026.
ABSTRACT Objective Chronic rhinosinusitis (CRS) is prevalent and causes a great negative impact on quality of life. Primary antibody deficiency (PAD) is highly prevalent with CRS compared to the background population. There are efficient treatment options to consider when CRS is a symptom of PAD. The condition seems to be underdiagnosed.
Anita García Petersen, Kasra Zainali‐Gill, Carsten Schade Larsen, Christian Nielsen, Therese Ovesen   +4 more
wiley   +1 more source

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, Volume 59, Issue 1, January 2026.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source

Pharmacotherapy Risks in Rare Genetic Diseases: Cross‐Referencing ACMG Secondary Findings v3.2 List With Clinical Databases

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Clinical genomics and pharmacogenomics have largely remained separate fields, though some genetic variants have overlapping disease risk and drug implications. However, the extent of this overlap is not well studied. To explore this gap, we cross‐referenced genes from the American College of Medical Genetics Secondary Findings v3.2 list with ...
Josiah D. Allen, Benjamin Q. Duong, Jordan Brady, Pamela Arn   +3 more
wiley   +1 more source

Dupilumab for atopic manifestations in pediatric patients with inborn errors of immunity: efficacy and safety in a genetically diverse cohort. [PDF]

Front Immunol
Alsediq N, Algholaiqa T, Alnami G, AlJaber AN.   +3 more
europepmc   +1 more source

Density Dependence During Evolutionary Rescue Increases Extinction Risk but Does Not Prevent Adaptation

Ecology Letters, Volume 29, Issue 1, January 2026.
This study investigates how density dependence influences evolutionary rescue in populations facing environmental stress. We found that while density dependence increases extinction risk by limiting population growth, it does not prevent adaptation in surviving populations.
Laure Olazcuaga, Brett A. Melbourne, Scott W. Nordstrom, Ruth A. Hufbauer   +3 more
wiley   +1 more source